3-[4-[2-(3,4-dihydro-2H-quinolin-1-yl)ethoxy]phenyl]-2-ethoxypropanoic acid

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 苯丙酸
• 英文名称: 3-[4-[2-(3,4-dihydro-2H-quinolin-1-yl)ethoxy]phenyl]-2-ethoxypropanoic acid
• 化学式: C₂₂H₂₇NO₄
• 分子量: 369.5
• InChiKey: PQMRQSQLBIMQGC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  27
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  59
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• [EN] TETRAHYDROQUINOLINE DERIVATIVES AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM<br/>[FR] DERIVES DE TETRAHYDROQUINOLINE ET LEUR UTILISATION EN MEDECINE, PROCEDE DE PREPARATION ASSOCIE ET COMPOSITIONS PHARMACEUTIQUES CONTENANT LESDITS COMPOSES
  申请人：REDDYS LAB LTD DR

  公开号：WO2003006022A1

  公开（公告）日：2003-01-23

  The present invention relates to novel antidiabetic, hypolipidemic, antiobesity and hypocholesterolemic compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. More particularly, the present invention relates to novel β-aryl-α-oxysubstituted alkylcarboxylic acids of the general formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them.