3-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)-4,6-dimethoxybenzaldehyde oxime

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 3-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)-4,6-dimethoxybenzaldehyde oxime
• 英文别名: (NE)-N-[[2,4-dimethoxy-5-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)phenyl]methylidene]hydroxylamine
• 化学式: C₂₄H₃₁NO₃
• 分子量: 381.515
• InChiKey: IEQFVJLASNEFLM-AFUMVMLFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  28
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  51
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Oxime derivatives for the treatment of dyslipidemia and hypercholesteremia
  申请人：——

  公开号：US20030083357A1

  公开（公告）日：2003-05-01

  The present invention relates to compounds of Formula (I) which may be useful in the treatment of diseases, such as, metabolic disorders, dyslipidemia and/or hyperchloesterolemia: 1

  本发明涉及Formula (I)的化合物，可能在治疗疾病，如代谢紊乱、血脂异常和/或高胆固醇血症方面有用：
• OXIME DERIVATIVES FOR THE TREATMENT OF DYSLIPIDEMIA AND HYPERCHOLESTEREMIA
  申请人：Incyte San Diego Incorporated

  公开号：EP1421061A1

  公开（公告）日：2004-05-26
• EP1421061A4
  申请人：——

  公开号：EP1421061A4

  公开（公告）日：2004-12-22
• [EN] OXIME DERIVATIVES FOR THE TREATMENT OF DYSLIPIDEMIA AND HYPERCHOLESTEREMIA<br/>[FR] DERIVES D'OXIME POUR LE TRAITEMENT DE LA DYSLIPIDEMIE ET DE L'HYPERCHOLESTEROLEMIE
  申请人：MAXIA PHARMACEUTICALS INC

  公开号：WO2003016267A1

  公开（公告）日：2003-02-27

  The present invention relates to compounds of Formula (I) which may be useful in the treatment of diseases, such as, metabolic disorders, dyslipidemia and/or hypercholesteremia: (I).