2,3-Bis(phenylimino)-5,6-dihydro-imidazo<2,1-b>thiazolidin

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并噻唑类
• 英文名称: 2,3-Bis(phenylimino)-5,6-dihydro-imidazo<2,1-b>thiazolidin
• 英文别名: N-(3-(Phenylimino)-5,6-dihydroimidazo[2,1-b][1,3]thiazol-2(3H)-ylidene)aniline；2-N,3-N-diphenyl-5,6-dihydroimidazo[2,1-b][1,3]thiazole-2,3-diimine
• 化学式: C₁₇H₁₄N₄S
• 分子量: 306.391
• InChiKey: GFBWUJYYTUBVSP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  22
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  65.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  亚乙基硫脲 、 bis(phenylimidoyl)chloride 在 三乙胺 作用下， 反应 2.0h， 以75%的产率得到2,3-Bis(phenylimino)-5,6-dihydro-imidazo<2,1-b>thiazolidin
  参考文献：
  名称：

  1,3-Acylumlagerungen bei der Cyclisierung von Thioharnstoffen mit Imidoylchloriden der Oxals�ure - Ein Zugang zu interessanten Thiocarbonylsystemen

  摘要：

  By cycloacylation of various substituted thioureas with bis-imidochlorides of oxalic acid the new thiazolidines 3, 4 and isomeric imidazolidines 5, 6 are obtained. Especially when triethylamine is used as a base the main products are the deeply coloured 4-arylimino-5-thioxo-imidazolidines which can be regarded as s-cis-configurated 1,4-dihetero-1,3-dienes. Some thiazolidines can be rearranged by means of anhydrous organic acids to parabanic acid derivatives; whereas the 5-thioxo-imidazolidines result from an intramolecular 1,3-acyl rearrangement during the reaction.

  DOI：

  10.1002/prac.19923340711

文献信息

• 1,3-Acylumlagerungen bei der Cyclisierung von Thioharnstoffen mit Imidoylchloriden der Oxals�ure - Ein Zugang zu interessanten Thiocarbonylsystemen
  作者：R. Beckert、M. Gruner

  DOI：10.1002/prac.19923340711

  日期：——

  By cycloacylation of various substituted thioureas with bis-imidochlorides of oxalic acid the new thiazolidines 3, 4 and isomeric imidazolidines 5, 6 are obtained. Especially when triethylamine is used as a base the main products are the deeply coloured 4-arylimino-5-thioxo-imidazolidines which can be regarded as s-cis-configurated 1,4-dihetero-1,3-dienes. Some thiazolidines can be rearranged by means of anhydrous organic acids to parabanic acid derivatives; whereas the 5-thioxo-imidazolidines result from an intramolecular 1,3-acyl rearrangement during the reaction.