(N,N-dimethylamino)-naphthalene-o-tert-butylphenol-1-sulfonamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: (N,N-dimethylamino)-naphthalene-o-tert-butylphenol-1-sulfonamide
• 英文别名: (4-Tert-butylphenyl) 5-(dimethylamino)naphthalene-1-sulfonate
• 化学式: C₂₂H₂₅NO₃S
• 分子量: 383.511
• InChiKey: GBSWIOZBIUZWPS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  55
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  4-叔丁基苯酚 、 丹酰氯 在 potassium carbonate 作用下， 以 二氯甲烷 为溶剂， 以35%的产率得到(N,N-dimethylamino)-naphthalene-o-tert-butylphenol-1-sulfonamide
  参考文献：
  名称：

  基于具有丹磺酰基部分的部分圆锥构象的杯[4]芳烃，基于比例感测Hg2 +。

  摘要：

  合成了一种新的荧光化学传感器，其基于具有丹磺酰基部分的部分圆锥构象的杯[4]芳烃。化学传感器展示了两种对比模式下Hg（2+）和Cu（2+）的选择性光学识别。该受体在Hg（2+）和Cu（2+）存在下表现出比例感测的Hg（2+）和“ ON-OFF”类型的荧光行为。该化合物表现为Hg（2+）和Cu（2+）离子的化学输入后的荧光分子开关。

  DOI：

  10.1021/ol801984y

文献信息

• Novel dansyl-appended calix[4]arene frameworks: fluorescence properties and mercury sensing
  作者：Shubha Pandey、Amir Azam、Siddharth Pandey、H. M. Chawla

  DOI：10.1039/b815379e

  日期：——

  Covalently-attached fluorophores may impart enhanced chemosensing capabilities to calixarene frameworks. Synthesis and characterization of six novel dansyl-appended calix[4]arenes, namely, H/Dan4, NO2/Dan4, H/(OH)2Dan2, H/(Ester)2(Dan)2, t-Bu/(OH)2Dan2, and t-Bu/(Ester)2Dan2, containing two or four dansyl moieties are reported. Among these, fluorescence intensity of NO2/Dan4 is observed to decrease

  共价连接的荧光团可以赋予杯芳烃骨架增强的化学传感能力。六种新的丹酰芳烃杯[4]芳烃的合成与表征，即H / Dan 4，NO 2 / Dan 4，H / （OH）2 Dan 2，H / （Ester）2（Dan）2，t- Bu / （OH）2 Dan 2和t-Bu / （Ester）2 Dan 2据报道，其含有两个或四个丹磺酰基部分。其中，在溶液中存在Hg 2+的情况下，观察到NO 2 / Dan 4的荧光强度显着降低。基于荧光的降低，Hg 2+的检出限为20 ppb。NO 2 / Dan 4作为Hg 2+的化学传感剂显示出优异的选择性和足够的可逆性。使用荧光光谱法研究了NO 2 / Dan 4与Hg 2+的络合，观察结果为2：1。（NO的形成常数2 / Dan 4） 2 Hg 2+在环境条件下估计为5.2（±0.8）×10 10 M -2。这些观察结果可归因于以下事实：虽然所有其他丹磺酰基
• Dansylation of Endocrine-disrupting Alkylphenolic Compounds on the Solid Phase Used for Extraction from Environmental Water
  作者：Bunji Uno、Jiro Katsumi、Kazumi Aoki

  DOI：10.1246/cl.2004.1584

  日期：2004.12

  The dansylation reaction of endocrine-disruptive alkylphenols on a C18-modified silica gel (ODS) instead of organic solvents was investigated with the aim of developing an environment-friendly and ...

  研究了内分泌干扰性烷基酚在 C18 改性硅胶 (ODS) 上而不是有机溶剂上的丹磺酰化反应，目的是开发一种环境友好、...
• Fluorescence Ratiometric Selective Recognition of Cu²⁺ Ions by Dansyl−Naphthalimide Dyads
  作者：Vadakkancheril S. Jisha、Anu J. Thomas、Danaboyina Ramaiah

  DOI：10.1021/jo901164w

  日期：2009.9.4

  Chimeric dyads 1a and 1b based on dansyl and naphthalimide units linked through the polymethylene group were synthesized, and their photophysical and interactions with various metal ions were investigated under different conditions, These dyads showed dual emission centered at around 375 and 525 rim, respectively, due to the locally excited state of the naphthalimide chromophore and energy-transfer-mediated emission (FRET) from the dansyl moiety. When titrated with various metal ions, these systems exhibited Unusual selectivity for Cu2+, ions as compared to Na+, Li+, K+, Zn2+, Pb2+, Hg2+, Co2+, Fe2+, Cd2+, Mg2+, and Ba2+ ions and signaled the binding event through inhibition of FRET mediated emission at 525 nm with concurrent enhancement in the emission intensity of the naphthalimide chromophore at 375 nm. The uniqueness of these dyads is that they form stable 2:1 stoichiometric complexes involving sulfonamide functionality and act as visual fluorescence ratiometric probes for the selective recognition of Cu2+ ions.
• SELECTIVE AND SENSITIVE DETECTION OF MERCURIC ION BY NOVEL DANSYL-APPENDED CALIX[4]ARENE MOLECULES, VIA FLUORESCENCE QUENCHING
  申请人：Pandey Siddharth

  公开号：US20110117657A1

  公开（公告）日：2011-05-19

  In particular, Compounds of Formula I or Formula II, generally known as calix[4]arenes, may be prepared. The compounds may be used to test samples for the presence of Hg 2+ by fluorescence quenching. The compounds may also be used to selectively detect Hg 2+ in samples containing other mono- or divalent metals.
• US8124416B2
  申请人：——

  公开号：US8124416B2

  公开（公告）日：2012-02-28