2-(1'-methyl-2'-hydroxypropoxy)-4,5-dimethyl-1,3,2-dioxyphospholane

• 分子结构分类: 有机化合物 - 有机磷化合物 - 亚磷酸三烷基酯
• 英文名称: 2-(1'-methyl-2'-hydroxypropoxy)-4,5-dimethyl-1,3,2-dioxyphospholane
• 英文别名: 3-[(4,5-Dimethyl-1,3,2-dioxaphospholan-2-yl)oxy]butan-2-ol
• 化学式: C₈H₁₇O₄P
• 分子量: 208.194
• InChiKey: HYBHKYOOHLHMIC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  47.9
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2-acetyl-5-methyl-1,2,3-diazaphosphole 、 (rac)-butane-2,3-diol 以 苯 为溶剂， 反应 72.0h， 生成 乙酸 2-(1-甲基乙亚基)酰肼 、 5-hydro-2,3,7,8-tetramethyl-1,4,6,9-tetraoxa-5-phosphaspiro[4,4]nonane 、 2-(1'-methyl-2'-hydroxypropoxy)-4,5-dimethyl-1,3,2-dioxyphospholane
  参考文献：
  名称：

  Reaction of 2-acetyl-5-methyl-2H-1,2,3-diazaphosphole with butane-2,3-diol

  摘要：

  The reaction of 2-acetyl-5-methyl-2H-1,2,3-diazaphosphole with (rac)-butane-2,3-diol at temperatures below 0 degreesC leads to the formation of a hydrospirophosphorane containing both a diazaphospholene and a dioxaphospholane ring system and a beta-hydroxyalkoxy-1,2,3-diazaphospholene. On heating, these products form a hydrospirotetraoxaphosphorane, its tautomeric monocyclic beta-hydroxyalkylphosphite and N-acetyl-N'-isopropylidene-hydrazine.

  DOI：

  10.1070/mc2004v014n05abeh001926

文献信息

• Reaction of 2-acetyl-5-methyl-2H-1,2,3-diazaphosphole with butane-2,3-diol
  作者：Narkis G. Khusainova、Olga A. Mostovaya、Nail M. Azancheev、Igor A. Litvinov、Dmitry B. Krivolapov、Rafael A. Cherkasov

  DOI：10.1070/mc2004v014n05abeh001926

  日期：2004.1

  The reaction of 2-acetyl-5-methyl-2H-1,2,3-diazaphosphole with (rac)-butane-2,3-diol at temperatures below 0 degreesC leads to the formation of a hydrospirophosphorane containing both a diazaphospholene and a dioxaphospholane ring system and a beta-hydroxyalkoxy-1,2,3-diazaphospholene. On heating, these products form a hydrospirotetraoxaphosphorane, its tautomeric monocyclic beta-hydroxyalkylphosphite and N-acetyl-N'-isopropylidene-hydrazine.