sodium;2-[(2Z)-2-[3-[(2,4-dimethylphenyl)carbamoyl]-2-oxonaphthalen-1-ylidene]hydrazinyl]-4-sulfophenolate

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: sodium;2-[(2Z)-2-[3-[(2,4-dimethylphenyl)carbamoyl]-2-oxonaphthalen-1-ylidene]hydrazinyl]-4-sulfophenolate
• 化学式: C25H20N3NaO6S
• 分子量: 513.5
• InChiKey: LPXSXFXFNSMAOI-MCOPDZHSSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  0.34
• 重原子数：
  36
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  156
• 氢给体数：
  3
• 氢受体数：
  8

文献信息

• Method of preparing integral multilayer analytical element
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：EP0254202A1

  公开（公告）日：1988-01-27

  A method of preparing an integral multilayer analytical element such as for analysis of calcium comprising a water-impermeable light-transmissive support, a reagent layer containing a water-soluble indicator capable of reacting with an analyte to produce an optically detectable change, and a porous spreading layer containing a spreading action controller and/or an acid capable of decomposing the calcium compounds in a sample, superposed in this order, which is characterized in that dissolving the spreading action controller and/or the acid in an organic solvent which does not dissolve the above water-soluble indicator, incorporating this solution into the porous spreading layer, and drying this superposed material.

  一种制备整体多层分析元件（如用于钙分析）的方法，该元件包括一个透光的不透水支撑层，一个试剂层，该试剂层含有一个能与被分析物反应产生光学可检测变化的水溶性指示剂，以及一个多孔铺展层，该多孔铺展层含有一个铺展作用控制剂和/或一个能分解样品中钙化合物的酸，这些试剂层依次叠加，其特征在于：将铺展作用控制剂和/或酸溶解在一个不溶解上述水溶性指示剂的有机溶剂中，将该溶液加入多孔铺展层中，并干燥该叠加材料。
• Methods for coating surfaces with antimicrobial agents
  申请人：The Board of Regents of the University of Texas System

  公开号：US10589003B2

  公开（公告）日：2020-03-17

  Disclosed are methods for coating or impregnating a surface with an antimicrobial agent that involve contacting the surface with a composition that includes an antimicrobial agent and a solvent, and curing the surface by applying heat. Also disclosed are methods for reducing the risk of development or progression of an infection in a subject in need of a medical device, that involve coating or impregnating a surface of the medical device with an antimicrobial agent and then curing the surface by applying heat, wherein the risk of development or progression of an infection is reduced.

  本发明公开了用抗菌剂涂覆或浸渍表面的方法，包括用包括抗菌剂和溶剂的组合物接触表面，并通过加热固化表面。还公开了降低需要使用医疗器械的受试者发生或恶化感染风险的方法，包括用抗菌剂涂覆或浸渍医疗器械表面，然后通过加热固化表面，从而降低发生或恶化感染的风险。
• Methods for coating and impregnating medical devices with antiseptic compositions
  申请人：Raad Issam

  公开号：US20050197634A1

  公开（公告）日：2005-09-08

  The present invention provides methods of coating or impregnating medical devices with an antiseptic composition that will inhibit or prevent the nosocomial infections typically associated with the use of such medical devices. The present invention further provides methods of coating or impregnating medical devices that produce devices with effective activity against infection, while avoiding destroying the devices or causing the devices to become toxic. In addition, the invention provides medical devices coated or impregnated with antiseptic compositions by the aforementioned novel methods.
• METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS
  申请人：RAAD ISSAM

  公开号：US20070154621A1

  公开（公告）日：2007-07-05

  Disclosed are methods for coating or impregnating a surface with an antimicrobial agent that involve contacting the surface with a composition that includes an antimicrobial agent and a solvent, and curing the surface by applying heat. Also disclosed are methods for reducing the risk of development or progression of an infection in a subject in need of a medical device, that involve coating or impregnating a surface of the medical device with an antimicrobial agent and then curing the surface by applying heat, wherein the risk of development or progression of an infection is reduced.
• MEDICAL DEVICES WITH BROAD SPECTRUM ANTIMICROBIAL ACTIVITY
  申请人：Raad Issam

  公开号：US20080183152A1

  公开（公告）日：2008-07-31

  The present invention provides novel broad spectrum antiseptic compounds that further have properties that allow them to be coated/impregnated into polymer surfaces. Methods for coating these antiseptic compounds onto medical devices especially indwelling medical devices to prevent the growth of pathogens in such devices and hence, to prevent infection to patients via such devices are provided. The invention also provides antiseptics that are useful as general surface disinfectants and sterilizers, fluid disinfectants and biocide preservatives.