(6aR,10aR)-3-己基-6,6,9-三甲基-6a,7,8,10a-四氢苯并[c]苯并吡喃-1-醇 | 36482-24-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 中文名称: (6aR,10aR)-3-己基-6,6,9-三甲基-6a,7,8,10a-四氢苯并[c]苯并吡喃-1-醇
• 英文名称: (6aR,10aR)-3-hexyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol
• 英文别名: (5''-Methyl)-Δ¹-THC；(6aR,10aR)-3-hexyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol
• CAS: 36482-24-3
• 化学式: C₂₂H₃₂O₂
• 分子量: 328.495
• InChiKey: DMJVNNFBMZZLFB-QZTJIDSGSA-N

物化性质

• 溶解度：
  DMF：50mg/mL； DMSO：60mg/mL； DMSO:PBS (pH 7.2) (1:3)：0.25 mg/ml；乙醇：35mg/mL；甲醇：30mg/mL

计算性质

• 辛醇/水分配系数(LogP)：
  7.5
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] CATALYTIC CANNABINOID PROCESSES AND PRECURSORS<br/>[FR] PROCÉDÉS ET PRÉCURSEURS DE CANNABINOÏDES CATALYTIQUES
  申请人：KARE CHEMICAL TECH INC

  公开号：WO2020232545A1

  公开（公告）日：2020-11-26

  The present disclosure relates to new cannabinoid sulfonate esters and processes for their use to prepare cannabinoids. The disclosure also relates to the use of catalysts and catalytic processes for the preparation of cannabinoids from the cannabinoid sulfonate esters.

  本公开涉及新的大麻素磺酸酯和它们的制备大麻素的过程。该公开还涉及使用催化剂和催化过程从大麻素磺酸酯制备大麻素。
• CANNABINERGIC NITRATE ESTERS AND RELATED ANALOGS
  申请人：Northeastern University

  公开号：US20160002195A1

  公开（公告）日：2016-01-07

  The present technology relates to novel cannabinergic nitrate esters and related analogs, process of preparation, pharmaceutical compositions and their methods of use as medicaments, pharmacological tools and/or biomarkers. The novel cannabinergic nitrate ester compounds provide medicaments useful in treating a variety of diseases and medical disorders.

  本技术涉及新型大麻素硝酸酯及其类似物、制备方法、制药组合物及其作为药物、药理工具和/或生物标志物的使用方法。这些新型大麻素硝酸酯化合物提供了治疗各种疾病和医学障碍的有用药物。
• Cannabinergic Nitrate Esters And Related Analogs
  申请人：Northeastern University

  公开号：US20170210728A1

  公开（公告）日：2017-07-27

  The present technology relates to novel cannabinergic nitrate esters and related analogs, process of preparation, pharmaceutical compositions and their methods of use as medicaments, pharmacological tools and/or biomarkers. The novel cannabinergic nitrate ester compounds provide medicaments useful in treating a variety of diseases and medical disorders.
• CATALYTIC CANNABINOID PROCESSES AND PRECURSORS
  申请人：KARE CHEMICAL TECHNOLOGIES INC.

  公开号：US20220220089A1

  公开（公告）日：2022-07-14

  The present disclosure relates to new cannabinoid sulfonate esters and processes for their use to prepare cannabinoids. The disclosure also relates to the use of catalysts and catalytic processes for the preparation of cannabinoids from the cannabinoid sulfonate esters.
• US9580400B2
  申请人：——

  公开号：US9580400B2

  公开（公告）日：2017-02-28