1,6,6,9-Tetramethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromene

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 1,6,6,9-Tetramethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromene
• 化学式: C₂₂H₃₂O
• 分子量: 312.5
• InChiKey: YBZVLDCAEOEOBU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.7
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• STABILIZED FORMULATIONS OF CANNABINOID COMPOSITIONS
  申请人：Berl Volker

  公开号：US20200138772A1

  公开（公告）日：2020-05-07

  In one embodiment, the present application discloses powder and aqueous formulations comprising a stabilized, aqueous purified cannabis oil emulsion comprising: a) CBD and THC wherein the ratio of CBD:THC by wt/wt is from 1,050:1 to 1:1,050, and b) at least one emulsifier selected from the group consisting of Poloxamer 188, Polysorbate 80, Polysorbate 20, Vit E-TPGS (TPGS), TPGS-1000, TPGS-750-M, Solutol HS 15, PEG-40 hydrogenated castor oil, PEG-35 Castor oil, PEG-8-glyceryl capylate/caprate, PEG-32-glyceryl laurate, PEG-32-glyceryl palmitostearate, Polysorbate 85, polyglyceryl-6-dioleate, sorbitan monooleate, Capmul MCM, Maisine 35-1, glyceryl monooleate, glyceryl monolinoleate, PEG-6-glyceryl oleate, PEG-6-glyceryl linoleate, oleic acid, linoleic acid, propylene glycol monocaprylate, propylene glycol monolaurate, polyglyceryl-3 dioleate, polyglyceryl-3 diisostearate and lecithin with and without bile salts, and mixtures thereof; and the uses in the treatment of diseases.
• PRODUCTION OF CANNABINOIDS IN YEAST
  申请人：BIOMEDICAN, INC.

  公开号：US20210403965A1

  公开（公告）日：2021-12-30

  The present disclosure relates to the production of cannabinoids in yeast. In as aspect there is provided a genetically modified yeast comprising: one or more GPP producing genes and optionally, one or more GPP pathway genes; two or more olivetolic acid producing genes; one or more cannabinoid precursor or cannabinoid producing genes; one or more Hexanoyl-CoA producing genes, and at least 5% dry weight of fatty acids or fats.
• [EN] COCRYSTALS OF CANNABINOIDS<br/>[FR] CO-CRISTAUX DE CANNABINOÏDES
  申请人：PURISYS LLC

  公开号：WO2021138610A1

  公开（公告）日：2021-07-08

  Described herein are cocrystals comprising a coformer and a cannabinoid selected from the group consisting of cannabinol and tetrahydrocannabinol. In certain embodiments, the coformer is tetramethylpyrazine, L-proline, or D-proline. Further described are methods of preparing the cocrystals starting from a cannabinoid oil and pharmaceutical compositions comprising the cocrystals.