7-[3-(4-Carbamoyl-3-methoxy-2-propyl-phenoxy)-propoxy]-8-propyl-chroman-2-carboxylic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 7-[3-(4-Carbamoyl-3-methoxy-2-propyl-phenoxy)-propoxy]-8-propyl-chroman-2-carboxylic acid
• 英文别名: 7-[3-(4-carbamoyl-3-methoxy-2-propylphenoxy)propoxy]-8-propyl-3,4-dihydro-2H-chromene-2-carboxylic acid
• 化学式: C₂₇H₃₅NO₇
• 分子量: 485.6
• InChiKey: LGHMHOHMGCTKDT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  35
• 可旋转键数：
  13
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  117
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• Methods for Treating Pruritis
  申请人：The Regents of the University of California

  公开号：US20190216790A1

  公开（公告）日：2019-07-18

  The present disclosure provides compositions and methods for treating chronic itch.
• [EN] ONCOLYTIC COMBINATIONS FOR THE TREATMENT OF CANCER<br/>[FR] COMBINAISONS ONCOLYTIQUES POUR TRAITEMENT DES CANCERS
  申请人：LILLY CO ELI

  公开号：WO2001034133A2

  公开（公告）日：2001-05-17

  The therapeutic combinations of leukotriene (LTB4) inhibitors and anti-cancer agents are disclosed. A method of treating cancer using leukotriene (LTB4) inhibitors in conjunction with anti-cancer agents is also disclosed.
• [EN] ONCOLYTIC COMBINATIONS FOR THE TREATMENT OF CANCER<br/>[FR] COMBINAISONS ONCOLYTIQUES POUR TRAITEMENT DU CANCER
  申请人：LILLY CO ELI

  公开号：WO2001034134A2

  公开（公告）日：2001-05-17

  Leukotriene (LTB4) antagonists enhance the effectiveness of 2',2'-difluoronucleoside anti-cancer agents.
• [EN] ONCOLYTIC COMBINATIONS FOR THE TREATMENT OF CANCER<br/>[FR] COMBINAISONS ONCOLYTIQUES POUR LE TRAITEMENT DU CANCER
  申请人：LILLY CO ELI

  公开号：WO2001034199A2

  公开（公告）日：2001-05-17

  A method of treating cancer with radiation, in conjunction with the administration of a leukotriene (LTB4) antagonist is disclosed.