3-[6-[(2R)-2-hydroxy-4-pyridin-3-ylbutoxy]naphthalen-2-yl]propyl 3-cyanopropanoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 3-[6-[(2R)-2-hydroxy-4-pyridin-3-ylbutoxy]naphthalen-2-yl]propyl 3-cyanopropanoate
• 化学式: C₂₆H₂₈N₂O₄
• 分子量: 432.5
• InChiKey: MAIAFJQRDLAVEF-XMMPIXPASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  32
• 可旋转键数：
  13
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  92.4
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• [EN] NOVEL COMPOUNDS<br/>[FR] NOUVEAUX COMPOSES
  申请人：ASTRAZENECA AB

  公开号：WO2000056714A1

  公开（公告）日：2000-09-28

  The invention relates to novel pyridyl derivatives (I), their use as medicaments, pharmaceutical formulations including them and methods for their preparation. The compounds of the invention are useful because they possess pharmacological activity and more particularly activity in the modulation of inflammatory and allergic conditions.