methyl N-[[4-bromo-7,7,8,8-tetrafluoro-2-(trifluoromethyl)-[1,4]dioxino[2,3-g]benzimidazol-1-yl]methyl]-N-ethylcarbamate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并二恶烷
• 英文名称: methyl N-[[4-bromo-7,7,8,8-tetrafluoro-2-(trifluoromethyl)-[1,4]dioxino[2,3-g]benzimidazol-1-yl]methyl]-N-ethylcarbamate
• 化学式: C₁₅H₁₁BrF₇N₃O₄
• 分子量: 510.16
• InChiKey: NKBJWYPFPDTIGV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  30
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  65.8
• 氢给体数：
  0
• 氢受体数：
  12

文献信息

• SUBSTITUIERTE BENZIMIDAZOLE ZUR BEHANDLUNG DER HISTOMIASIS
  申请人：Bayer Animal Health GmbH

  公开号：EP1835912B1

  公开（公告）日：2009-08-26
• Substituted benzimidazoles, production and use thereof as agents for combating parasitic protozoas
  申请人：Greif Gisela

  公开号：US20070066671A1

  公开（公告）日：2007-03-22

  The present invention relates to new substituted benzimidazoles, their preparation and their use as agents against parasitic protozoa. The active compounds are characterized by the following formula (I): in which X 1 represents chlorine or bromine, R 1 represents hydrogen or C 1-4 -alkyl, R 3 represents fluoroalkyl, R 2 represents the radical R 4 represents alkyl or substituted phenyl, R 5 represents alkyl.
• Novel Antiparasitic Combination of Active Compounds
  申请人：Greif Gisela

  公开号：US20070232609A1

  公开（公告）日：2007-10-04

  The present invention relates to the combined use of substituted benzimidazoles and 1,2,4-triazine compounds against parasitic protozoa, in particular coccidia.
• SUBSTITUTED BENZIMIDAZOLES FOR TREATMENT OF HISTOMONIASIS
  申请人：Greif Gisela

  公开号：US20090131493A1

  公开（公告）日：2009-05-21

  The present invention relates to the use of substituted benzimidazoles for controlling histomoniasis, especially in turkeys.