1,1,2,2-四氟-1-(三氟甲氧基)乙烷 | 2356-61-8

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代烷
• 中文名称: 1,1,2,2-四氟-1-(三氟甲氧基)乙烷
• 英文名称: trifluoromethyl-1H-pentafluoroethyl ether
• 英文别名: 2-hydryl-F-ethyl F-methyl ether；1-trifluoromethoxy-1,1,2,2-tetrafluoroethane；1,1,2,2-Tetrafluor-2-trifluormethoxy-aethan；1,1,2,2-Tetrafluoro-1-(trifluoromethoxy)ethane
• CAS: 2356-61-8
• 化学式: C₃HF₇O
• 分子量: 186.029
• InChiKey: MEVYDFZGEHEVSM-UHFFFAOYSA-N

物化性质

• 熔点：
  -141.15°C
• 沸点：
  11.04°C (rough estimate)
• 密度：
  1.6684 (estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  8

安全信息

• 海关编码：
  2909199090

反应信息

• 作为反应物：
  描述：

  1,1,2,2-四氟-1-(三氟甲氧基)乙烷 在 三乙胺 作用下， 20.0~40.0 ℃ 、700.01 kPa 条件下， 反应 1.0h， 以1.17 kg的产率得到三氟甲基三氟乙烯基醚
  参考文献：
  名称：

  [EN] INDUSTRIAL PROCESS FOR MANUFACTURING OF PERFLUORO(METHYL VINYL ETHER) (PFMVE) AND OF 1,1,2,2-TETRAFLUORO-1-(TRIFLUOROMETHOXY)ETHANE (TFTFME)
  [FR] PROCÉDÉ INDUSTRIEL POUR FABRIQUER DU PERFLUORO(ÉTHER MÉTHYLVINYLIQUE) (PFMVE) ET DU 1,1,2,2-TÉTRAFLUORO-1-(TRIFLUOROMÉTHOXY)ÉTHANE (TFTFME)

  摘要：

  Disclosed is an industrial process for manufacturing of perfluoro(methyl vinyl ether) (PFMVE), and of 1,1,2,2-tetrafluoro-1-(trifluoromethoxy) ethane (TFTFME) (E 227), involving reactions in liquid phase and performing reactions, for example, in a (closed) column reactor or in a microreactor, respectively. Also disclosed is an industrial process for manufacturing of perfluoro(methyl vinyl ether) (PFMVE) by HF-elimination from the compound 1,1,2,2-tetrafluoro-1-(trifluoromethoxy) ethane (TFTFME) (E 227). Also disclosed is an industrial process for manufacturing of the compound 1,1,2,2-tetrafluoro-1-(trifluoromethoxy) ethane (TFTFME) (E 227) by selective fluorination of the compound HFE-254 (1,1,2,2-tetrafluoro-1-(methoxy) ethane), i.e., perfluorination of only the CH3O-group (i.e., methoxy-group) of the compound HFE-254 is selectively fluorinated to a CF3O-group (i.e., trifluorometh-oxy-group).

  公开号：

  WO2022111033A1
• 作为产物：
  描述：

  3-甲氧基丙酸甲酯 生成 1,1,2,2-四氟-1-(三氟甲氧基)乙烷
  参考文献：
  名称：

  Berenblit,V.V. et al., Journal of Organic Chemistry USSR (English Translation), 1976, vol. 12, p. 765 - 768

  摘要：

  DOI：

文献信息

• Compositions of a hydrofluoroether and a hydrofluorocarbon
  申请人：Klug Diana Lynn

  公开号：US06905630B2

  公开（公告）日：2005-06-14

  This invention relates to compositions that include at least one fluoroether and at least one hydrofluorocarbon. Included in this invention are compositions of a cyclic or acyclic hydrofluoroether of the formula C a F b H 2a+2−b O c wherein a=2 or 3 and 3≦b≦8 and c=1 or 2 and a hydrofluorocarbon of the formula C n F m H 2n+2−m wherein 1≦n≦4 and 1≦m≦8. Such compositions may be used as refrigerants, cleaning agents, expansion agents for polyolefins and polyurethanes, aerosol propellants, heat transfer media, gaseous dielectrics, fire extinguishing agents, power cycle working fluids, polymerization media, particulate removal fluids, carrier fluids, buffing abrasive agents, and displacement drying agents.

  这项发明涉及包括至少一种氟醚和至少一种氢氟烃的组合物。该发明包括具有下列式CaFbH2a+2−bOc的环状或非环状氢氟醚组合物，其中a=2或3，3≦b≦8，c=1或2，以及具有下列式CnFmH2n+2−m的氢氟烃组合物，其中1≦n≦4，1≦m≦8。这些组合物可用作制冷剂、清洁剂、聚烯烃和聚氨酯的膨胀剂、喷雾推进剂、传热介质、气体绝缘体、灭火剂、动力循环工作流体、聚合介质、颗粒去除流体、载体流体、抛光磨料剂和位移干燥剂。
• Gubanov, V. A.; Zevakin, I. A.; Gurari, V. E., Journal of Organic Chemistry USSR (English Translation), 1981, p. 1409 - 1412
  作者：Gubanov, V. A.、Zevakin, I. A.、Gurari, V. E.、Tumanova, A. V.、Dolgopol'skii, I. M.、et al.

  DOI：——

  日期：——
• Relative Rate Constants for the Reactions of CF3OF with Olefins in Solution
  作者：W. Navarrini、A. Russo、V. Tortelli

  DOI：10.1021/jo00125a033

  日期：1995.10

  The addition reactions of CF3OF to chloro fluoro olefins have been studied in solution at low temperature (-78, -105 degrees C), and their relative rate constants have been determined using the kinetic approach of competition reactions. The reactivity and regio- and stereoselectivity are consistent with a free radical chain-propagating reaction in which the alkenes are attacked by the CF3O. radical generated by homolitic cleavage of the O-F bond in the CF3OF molecule.
• Gubanov,V.A. et al., Journal of general chemistry of the USSR, 1964, vol. 34, p. 2825 - 2826
  作者：Gubanov,V.A. et al.

  DOI：——

  日期：——
• BERENBLIT V. V.; ZAPEVALOV A. YA.; PANITKOVA E. S.; PLASHKIN V. S.; RONDA+, ZH. ORGAN. XIMII, 1979, 15, HO 7, 1417-1425
  作者：BERENBLIT V. V.、 ZAPEVALOV A. YA.、 PANITKOVA E. S.、 PLASHKIN V. S.、 RONDA+

  DOI：——

  日期：——