(+/-)-5-(2-cyclopenta-1,3-dienyl)-9-fluoro-1,2-dihydro-2,2,4-trimethyl-5H-chromeno[3,4-f]quinoline | 1026973-96-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: (+/-)-5-(2-cyclopenta-1,3-dienyl)-9-fluoro-1,2-dihydro-2,2,4-trimethyl-5H-chromeno[3,4-f]quinoline
• 英文别名: 5-Cyclopenta-1,4-dien-1-yl-9-fluoro-2,2,4-trimethyl-1,5-dihydrochromeno[3,4-f]quinoline
• CAS: 1026973-96-5
• 化学式: C₂₄H₂₂FNO
• 分子量: 359.443
• InChiKey: DBNRNMZUFWQGHB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  27
• 可旋转键数：
  1
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  21.3
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• 5-cycloalkenyl 5H-chromeno[3,4-f]quinoline derivatives as selective progesterone receptor modulator compounds
  申请人：——

  公开号：US20040152718A1

  公开（公告）日：2004-08-05

  The present invention is directed to compounds, pharmaceutical compositions, and methods for modulating processes mediated by Progesterone Receptor. Also provided are methods of making such compounds and pharmaceutical compositions.

  本发明涉及调节由孕酮受体介导的过程的化合物、药物组合物和方法。还提供了制造此类化合物和药物组合物的方法。
• 5-Cycloalkenyl 5H-chromeno[3,4-f]quinoline derivatives as selective progesterone receptor modulator compounds
  申请人：Zhi Lin

  公开号：US20060194827A1

  公开（公告）日：2006-08-31

  The present invention relates to methods for modulating processes mediated by progesterone receptor using nonsteroidal compounds and compositions which may be high affinity, high specificity agonists, partial agonists (i.e., partial activators and/or tissue-specific activators) and/or antagonists for progesterone receptors.
• US7071205B2
  申请人：——

  公开号：US7071205B2

  公开（公告）日：2006-07-04