N'-[(1Z)-1-(1,2-dihydroacenaphthylen-5-yl)ethylidene]-2-phenylcyclopropanecarbohydrazide

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: N'-[(1Z)-1-(1,2-dihydroacenaphthylen-5-yl)ethylidene]-2-phenylcyclopropanecarbohydrazide
• 英文别名: N-[(Z)-1-(1,2-dihydroacenaphthylen-5-yl)ethylideneamino]-2-phenylcyclopropane-1-carboxamide
• 化学式: C₂₄H₂₂N₂O
• 分子量: 354.4
• InChiKey: GAMQTAJOMFTWOG-MYYYXRDXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  27
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  41.5
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Antiviral Drugs for Treatment of Arenavirus Infection
  申请人：Hruby Dennis E.

  公开号：US20090036513A1

  公开（公告）日：2009-02-05

  Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain novel compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by hemorrhagic fever viruses is disclosed, i.e., including but not limited to, Arenaviridae (Junin, Machupo, Guanarito, Sabia, Lassa, Tacaribe, and Pichinde), Filoviridae (Ebola and Marburg viruses), Flaviviridae (yellow fever, Omsk hemorrhagic fever and Kyasanur Forest disease viruses), and Bunyaviridae (Rift Valley fever).
• US8148428B2
  申请人：——

  公开号：US8148428B2

  公开（公告）日：2012-04-03
• US8492434B2
  申请人：——

  公开号：US8492434B2

  公开（公告）日：2013-07-23
• US9199920B2
  申请人：——

  公开号：US9199920B2

  公开（公告）日：2015-12-01