1-丁基-3,5-二甲基哌嗪 | 109055-59-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 中文名称: 1-丁基-3,5-二甲基哌嗪
• 英文名称: 1-Butyl-3,5-dimethylpiperazine
• CAS: 109055-59-6
• 化学式: C₁₀H₂₂N₂
• 分子量: 170.3
• InChiKey: SHKKUBZVEDHKGW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  15.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Pyrazolo[1,5-a]pyridine derivatives or pharmaceutically acceptable salts thereof
  申请人：Unoki Gen

  公开号：US20070072898A1

  公开（公告）日：2007-03-29

  A pyrazolo[1,5-a]pyridine derivative represented by formula (I) and salt thereof exhibit excellent MAPKAP-K2 inhibitory activity. Accordingly, medicines comprising this compound as an active ingredient are expected to be valuable for treating or preventing diseases mediated by MAPKAP-K2 such as inflammatory injury, autoimmune diseases, asteropathia destruens, cancer and/or growth of tumor.

  由式(I)表示的吡唑并[1,5-a]吡啶衍生物及其盐表现出优异的MAPKAP-K2抑制活性。因此，包含该化合物作为活性成分的药物预计对治疗或预防由MAPKAP-K2介导的疾病，如炎症损伤、自身免疫疾病、asteropathia destruens、癌症和/或肿瘤生长具有重要价值。
• PROCESS FOR PRODUCTION OF POLYESTER-CONTAINING FLEXIBLE POLYURETHANE FOAM, AND CATALYST COMPOSITION FOR USE IN THE PROCESS
  申请人：Tosoh Corporation

  公开号：EP2204394B1

  公开（公告）日：2017-07-12
• METHOD FOR PRODUCING POLYESTER TYPE FLEXIBLE POLYURETHANE FOAM, AND CATALYST COMPOSITION TO BE USED THEREFOR
  申请人：Takahashi Yoshihiro

  公开号：US20100256249A1

  公开（公告）日：2010-10-07

  To provide a method for producing a low-odor polyester-type flexible polyurethane foam which is excellent in formability and free from scorch in the interior of the foam, and further discharges substantially no volatile amine compound from a product, in the production of a polyester-type flexible polyurethane foam, and to provide a catalyst composition to be used for the production method. A polyester-type flexible polyurethane foam is produced by a process which comprises reacting a polyester polyol with a polyisocyanate, in the presence of a catalyst composition containing one or more amine compounds selected from the group consisting of an amine compound represented by the following formula (1): in the above formula (1), R 1 is a C 1-6 linear or branched alkyl group, and each of R 2 , R 3 , R 4 and R 5 which are independent of one another, is a hydrogen atom or a C 1-2 alkyl group, an amine compound represented by the following formula (2): in the above formula (2), R 6 is a C 2-6 linear or branched alkylene group, and an amine compound represented by the following formula (3): in the above formula (3), each of R 7 and R 8 which are independent of each other, is a C 1-4 alkyl group, and R 9 is a C 3-5 linear or branched alkylene group; a blowing agent; and a surfactant.
• US8980965B2
  申请人：——

  公开号：US8980965B2

  公开（公告）日：2015-03-17