1-吗啉基甲基萘-2,7-二醇 | 81653-20-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 中文名称: 1-吗啉基甲基萘-2,7-二醇
• 中文别名: 2-丙烯酸,2-甲基,丁基酯,聚合丁基2-丙烯酸酯,2-羟基丙基2-甲基-2-丙烯酸酯
• 英文名称: 1-morpholinomethyl-2,7-dihydroxynaphthalene
• 英文别名: 1-Morpholinomethylnaphthalene-2,7-diol；1-(morpholin-4-ylmethyl)naphthalene-2,7-diol
• CAS: 81653-20-5
• 化学式: C₁₅H₁₇NO₃
• 分子量: 259.305
• InChiKey: OXSKDKWXVKZOAT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  52.9
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1-吗啉基甲基萘-2,7-二醇 、 六乙基亚磷酸胺 以 1,4-二氧六环 、 乙腈 为溶剂， 反应 2.0h， 生成
  参考文献：
  名称：

  Phosphorylation of aminomethylated derivatives of 2,7-dihydroxynaphthalenes

  摘要：

  Phosphorylation of 2,7-dihydroxynaphthalene derivatives, containing different amine components was performed by full amides of phosphorous acid. A substantial effect of the intramolecular hydrogen bond on the process of phosphorylation was shown. Cyclophosphorylation was performed and principal possibility of the synthesis of naphthophosphacrownaphanes having aminomethyl linkers was shown. Mannich aminomethylation of naphthophosphacyclophanes was found to be impossible.

  DOI：

  10.1134/s1070363216030099
• 作为产物：
  描述：

  吗啉 、 聚合甲醛 、 2,7-二羟基萘 以 甲醇 、 水 为溶剂， 反应 24.0h， 以87%的产率得到1-吗啉基甲基萘-2,7-二醇
  参考文献：
  名称：

  Aminomethylated derivatives of 2,7-dihydroxynaphthalene

  摘要：

  DOI：

  10.1134/s0012500814070052

文献信息

• Phosphorylation of aminomethylated derivatives of 2,7-dihydroxynaphthalenes
  作者：P. V. Slitikov、E. N. Rasadkina

  DOI：10.1134/s1070363216030099

  日期：2016.3

  Phosphorylation of 2,7-dihydroxynaphthalene derivatives, containing different amine components was performed by full amides of phosphorous acid. A substantial effect of the intramolecular hydrogen bond on the process of phosphorylation was shown. Cyclophosphorylation was performed and principal possibility of the synthesis of naphthophosphacrownaphanes having aminomethyl linkers was shown. Mannich aminomethylation of naphthophosphacyclophanes was found to be impossible.
• Aminomethylated derivatives of 2,7-dihydroxynaphthalene
  作者：E. E. Nifant’ev、P. V. Slitikov、E. N. Rasadkina

  DOI：10.1134/s0012500814070052

  日期：2014.7