2,2-二甲基-3-(4-硫烷基苯基)丙酸 | 887354-80-5

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 苯丙酸
• 中文名称: 2,2-二甲基-3-(4-硫烷基苯基)丙酸
• 中文别名: 2,2-二甲基-3-(4-硫苯基)丙酸
• 英文名称: 2,2-Dimethyl-3-(4-mercaptophenyl)propionic acid
• 英文别名: 2,2-dimethyl-3-(4-sulfanylphenyl)propanoic acid
• CAS: 887354-80-5
• 化学式: C₁₁H₁₄O₂S
• mdl: MFCD02683322
• 分子量: 210.29
• InChiKey: XXDIJXPNRJHFRH-UHFFFAOYSA-N

物化性质

• 熔点：
  81-84°C
• 沸点：
  352.8±17.0 °C(Predicted)
• 密度：
  1.174±0.06 g/cm3(Predicted)
• 溶解度：
  可溶于氯仿、乙醇、甲醇

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.363
• 拓扑面积：
  38.3
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• CHEMICAL CONJUGATES FOR TARGETED DEGRADATION UNDER REDUCING CONDITIONS
  申请人：Baldwin Aaron

  公开号：US20130244975A1

  公开（公告）日：2013-09-19

  The present invention is related to compositions which can undergo targeted degradation under certain physiological reducing conditions. The compositions may, for example, be hydrogels in which maleimide-functionalized low molecular weight heparin is cross-linked with various thiol-functionalized polyethylene glycol multi-arm star polymers. Both the gelation and degradation of the hydrogels can be modified by careful selection of the thiol. For example, hydrogels prepared from aryl thiol-maleimide adducts can undergo a retro Michael addition-type reaction, leading to degradation of the composition and release of the bioactive molecule.
• US9044515B2
  申请人：——

  公开号：US9044515B2

  公开（公告）日：2015-06-02