3H-xanthene

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 3H-xanthene
• 英文别名: 3H-Xanthen
• 化学式: C₁₃H₁₀O
• 分子量: 182.222
• InChiKey: WANKCLVBRDARAX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  罗丹明B 在 indium zinc sulfide 作用下， 反应 1.5h， 生成 3H-xanthene 、 苯甲酸 、 苯酚
  参考文献：
  名称：

  Comparative study of the photocatalytic performance for the degradation of different dyes by ZnIn₂S₄: adsorption, active species, and pathways

  摘要：

  通过对基于ZnIn2S4的不同染料降解的光催化性能进行比较研究，重点考察染料吸附、活性物种和降解途径。

  DOI：

  10.1039/c7ra00199a

文献信息

• Fluorescent Nucleobase Conjugates Having Anionic Linkers
  申请人：TAING Meng

  公开号：US20090092986A1

  公开（公告）日：2009-04-09

  Provided are nucleotide-dye conjugates and related compounds in which a dye is linked to a nucleobase directly or indirectly by an anionic linker. The anionic character of the linker is provided by one or more anionic moieties which are present in the linker, such as phosphate, phosphonate, sulfonate, and carboxylate groups. When the dye is a provided as a donor/acceptor dye pair, the anionic linker can be located between the donor and the acceptor, or between the nucleobase and either the donor or acceptor, or both. In one embodiment, conjugates of the invention provide enhanced electrophoretic mobility characteristics to sequencing fragments, e.g., for dideoxy sequencing using labeled terminators.

  提供了核苷酸染料共轭物和相关化合物，其中染料通过阴离子连接基团直接或间接地与核碱基相连。连接基团的阴离子特性由存在于连接基团中的一个或多个阴离子基团提供，例如磷酸酯、膦酸酯、磺酸盐和羧酸盐基团。当染料作为给体/受体染料对提供时，阴离子连接基团可以位于给体和受体之间，或位于核碱基和给体或受体之间，或两者之间。在一种实施例中，本发明的共轭物提供了增强的电泳迁移特性，例如用标记的终止子进行二硫代氧核苷酸测序。
• PROPARGYL SUBSTITUTED NUCLEOSIDE COMPOUNDS AND METHODS
  申请人：ROSENBLUM Barnett B.

  公开号：US20100113759A1

  公开（公告）日：2010-05-06

  The present teachings relate to nucleobase, nucleoside and nucleotide compounds, methods of synthesis, and uses thereof. The present teachings provide compounds, such as nucleobase, nucleoside and/or nucleotide compounds including a propargyl linker, and methods for making or using such compounds.

  本教学涉及核碱基，核苷和核苷酸化合物，其合成方法和用途。本教学提供化合物，如包括丙炔基连接器的核碱基，核苷和/或核苷酸化合物，以及制备或使用这些化合物的方法。
• Propargyl Substituted Nucleoside Compounds and Methods
  申请人：ROSENBLUM Barnett B.

  公开号：US20120309953A1

  公开（公告）日：2012-12-06

  Disclosed, among other things, are compounds having the structure wherein X comprises a bond or a linker, LABEL comprises at least one detectable label, W 1 taken alone is —H or —OH, W 2 is —OH or a non-extendable moiety, W 3 when taken alone is —H or when taken together with W 1 is —CH 2 —O—, and W 4 is OH, monophosphate, diphosphate, or triphosphate. Also disclosed are labeled polynucleotide compounds and methods of use thereof.

  公开的东西包括以下结构的化合物：其中X包括一个键或一个连接物，LABEL包括至少一个可检测的标记，W1单独为-H或-OH，W2为-OH或不可延伸的基团，W3单独为-H或与W1一起为-CH2-O-，W4为OH、单磷酸、二磷酸或三磷酸。还公开了带标记的多核苷酸化合物及其使用方法。
• FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS
  申请人：Taing Meng

  公开号：US20100304381A1

  公开（公告）日：2010-12-02

  Provided are nucleotide-dye conjugates and related compounds in which a dye is linked to a nucleobase directly or indirectly by an anionic linker. The anionic character of the linker is provided by one or more anionic moieties which are present in the linker, such as phosphate, phosphonate, sulfonate, and carboxylate groups. When the dye is a provided as a donor/acceptor dye pair, the anionic linker can be located between the donor and the acceptor, or between the nucleobase and either the donor or acceptor, or both. In one embodiment, conjugates of the invention provide enhanced electrophoretic mobility characteristics to sequencing fragments, e.g., for dideoxy sequencing using labeled terminators.

  提供的是核苷酸染料共轭物和相关化合物，其中染料通过阴离子连接剂直接或间接地与核碱基相连。连接剂的阴离子特性由连接剂中存在的一个或多个阴离子基团提供，例如磷酸盐、膦酸盐、磺酸盐和羧酸盐基团。当染料作为给体/受体染料对提供时，阴离子连接剂可以位于给体和受体之间，或位于核碱基和给体或受体之间，或两者之间。在一种实施例中，本发明的共轭物提供了增强的电泳迁移特性，例如使用标记终止子进行二苯基测序的测序片段。
• Ligation and amplification reactions for determining target molecules
  申请人：Applied Biosystems, LLC

  公开号：EP2161346A1

  公开（公告）日：2010-03-10

  The present invention is directed to methods, reagents, and kits for detecting the presence or absence of (or quantifying) target polynucleotide sequences and proteins in at least one sample using encoding and decoding reactions. When a particular target polynucleotide is present in a sample for example, a reaction product is formed in the encoding reaction that includes addressable primer portions. At least one labeling probe and at least one address primer can be employed in the decoding amplification reaction thereby providing a detectable signal value depending upon whether a sequence is present or absent. In some embodiments, the encoding comprises a ligation reaction with linker probes, and single nucleotide polymorphisms (SNPs) are analyzed.

  本发明涉及使用编码和解码反应检测至少一个样品中目标多核苷酸序列和蛋白质存在与否（或定量）的方法、试剂和试剂盒。例如，当样品中存在特定的目标多核苷酸时，编码反应中会形成反应产物，其中包括可寻址的引物部分。至少一个标记探针和至少一个地址引物可用于解码扩增反应，从而根据序列是否存在提供可检测的信号值。在某些实施方案中，编码包括与连接探针的连接反应，并对单核苷酸多态性（SNP）进行分析。