4-[(1R,2R)-2-(2-naphthalen-2-ylethoxy)cyclohexyl]morpholine

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 4-[(1R,2R)-2-(2-naphthalen-2-ylethoxy)cyclohexyl]morpholine
• 化学式: C₂₂H₂₉NO₂
• 分子量: 339.5
• InChiKey: NWPBCZNZFCURCH-FGZHOGPDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  25
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  21.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF
  申请人：Bain Allen I.

  公开号：US20100029639A1

  公开（公告）日：2010-02-04

  Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.

  本发明揭示了离子通道调节化合物。本发明的化合物可以被用于制备组合物和工具包。本发明还揭示了化合物和组合物的多种体外和体内用途，包括治疗心律失常以及产生镇痛和局部麻醉的作用。
• AMINOCYCLOHEXYL ETHER COMPOUNDS AND USES THEREOF
  申请人：Nortran Pharmaceuticals Inc.

  公开号：EP1087934B1

  公开（公告）日：2004-02-25
• Ion channel modulating compounds and uses thereof
  申请人：Bain I. Allen

  公开号：US20070004718A1

  公开（公告）日：2007-01-04

  Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
• US7524879B2
  申请人：——

  公开号：US7524879B2

  公开（公告）日：2009-04-28
• US7534790B2
  申请人：——

  公开号：US7534790B2

  公开（公告）日：2009-05-19