(6aS,10aS)-6,6-dimethyl-3-(2-methyloctan-2-yl)-9-(pyrazol-1-ylmethyl)-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: (6aS,10aS)-6,6-dimethyl-3-(2-methyloctan-2-yl)-9-(pyrazol-1-ylmethyl)-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
• 化学式: C₂₈H₄₀N₂O₂
• 分子量: 436.6
• InChiKey: RCJNCCRIOFZSAV-GOTSBHOMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.2
• 重原子数：
  32
• 可旋转键数：
  8
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.61
• 拓扑面积：
  47.3
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• NOVEL NON-PSYCHOTROPIC CANNABINOIDS
  申请人：Garzon Aaron

  公开号：US20070213369A1

  公开（公告）日：2007-09-13

  Novel non-psychotropic cannabinoids are disclosed and pharmaceutical compositions comprising these novel compounds are described for preventing neurotoxicity, neuroinflammation, immune or inflammatory disorders comprising as active ingredient the stereospecific (+) enantiomer, having (3S,4S) configuration of Δ 6 tetrahydrocannabinol type compounds. The compositions are particularly effective in alleviating and even preventing neurotoxicity due to acute injuries to the central nervous system, including mechanical trauma, compromised or reduced blood supply as may occur in cardiac arrest or stroke, or poisonings. They are also effective in the treatment of certain inflammatory disorders and chronic degenerative diseases characterized by neuronal loss and chronic pain including neuropathic pain.
• US7235584B2
  申请人：——

  公开号：US7235584B2

  公开（公告）日：2007-06-26