1,10-Phenanthroline-4,7-disulfonic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 菲咯啉
• 英文名称: 1,10-Phenanthroline-4,7-disulfonic acid
• 化学式: C₁₂H₈N₂O₆S₂
• 分子量: 340.3
• InChiKey: MQEYHFQACCOUEO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  22
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  151
• 氢给体数：
  2
• 氢受体数：
  8

文献信息

• Electronically neutral metal complexes as biological labels
  申请人：Rubipy Scientific, Inc.

  公开号：US10203333B2

  公开（公告）日：2019-02-12

  The invention relates to electronically neutral metal complexes as luminescent labels. The positive charge of the metal ion in the complex is neutralized by the negatively charged groups that are covalently linked to the nitrogen-containing diimine ligands, such as 2,2-bipyridine, 1,10-phenanthroline and their derivatives. The electronic neutrality reduces the impact of the metal complexes on the biological and/or biochemical activities of the labeled biomolecules, while the intensity of luminescent emission under electrochemical excitation is enhanced. These luminescent metal complex labels are useful in bioanalytic methodology development, with luminescence as the signal modality, such as electrochemiluminescence.

  本发明涉及作为发光标签的电子中性金属配合物。络合物中金属离子的正电荷被与含氮二亚胺配体（如 2,2-联吡啶、1,10-菲罗啉及其衍生物）共价连接的带负电的基团中和。电子中性降低了金属复合物对标记生物大分子的生物和/或生化活性的影响，同时增强了电化学激发下的发光强度。这些发光金属复合物标签可用于开发以发光为信号模式（如电化学发光）的生物分析方法。
• METHOD FOR PRODUCING 3,3-DIMETHYL-2-(1-PROPENYL) CYCLOPROPANE CARBOXYLATE
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP1681282B1

  公开（公告）日：2013-01-23
• Method for producing 3, 3-dimethyl-2-(1-propenyl) cyclopropanecarboxylate
  申请人：Hagiya Koji

  公开号：US20070078278A1

  公开（公告）日：2007-04-05

  A method for producing 3,3-dimethyl-2-(1-propenyl)cyclopropanecarboxylate represented by the formula (2): wherein R 1 represent an optionally substituted alkyl group, an optionally substituted aryl group or an optionally substituted aralkyl group, which comprises a 3,3-dimethyl-2-(2-carboxy-1-propenyl)cyclopropanecarboxylate represented by the formula (1): wherein R 1 is as described above, is brought into contact with a copper compound and a nitrogen-containing aromatic compound, is provided.
• US6274806B1
  申请人：——

  公开号：US6274806B1

  公开（公告）日：2001-08-14
• US7393971B2
  申请人：——

  公开号：US7393971B2

  公开（公告）日：2008-07-01