methyl 7-cyclopentyloxy-6-methoxy-4-oxo-2,3-dihydro-1H-naphthalene-2-carboxylate

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: methyl 7-cyclopentyloxy-6-methoxy-4-oxo-2,3-dihydro-1H-naphthalene-2-carboxylate
• 化学式: C₁₈H₂₂O₅
• 分子量: 318.4
• InChiKey: ODTDCISCUGXCKM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  23
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  61.8
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• [EN] 2,6,7-SUBSTITUTED TETRALINES USEFUL FOR THE PREPARATION OF MEDICAMENTS WITH PHOSPHODIESTERASE IV INHIBITORY ACTIVITY<br/>[FR] TETRALINES 2,6,7-SUBSTITUEES CONVENANT A L'ELABORATION DE MEDICAMENTS INHIBITEURS DE LA PHOSPHODIESTERASE IV
  申请人：SIGMA TAU IND FARMACEUTI

  公开号：WO2002000609A2

  公开（公告）日：2002-01-03

  Formula (I) compounds are described where the groups are as defined in the description, as well as processes for their preparation and their use as medicaments, particularly for the preparation of medicaments with phosphodiesterase IV inhibitory activity.