(6R,7R)-6-(3,4-dihydroxyphenyl)-5,6,7,8-tetrahydronaphthalene-1,3,7-triol

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: (6R,7R)-6-(3,4-dihydroxyphenyl)-5,6,7,8-tetrahydronaphthalene-1,3,7-triol
• 化学式: C₁₆H₁₆O₅
• 分子量: 288.29
• InChiKey: IUIXNLXBIRTHMO-IAQYHMDHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  21
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  101
• 氢给体数：
  5
• 氢受体数：
  5

文献信息

• Compositions and Methods of Treatment With Proanthocyanidin Polymer Antidiarrheal Compositions
  申请人：Rozhon Edward James

  公开号：US20090148397A1

  公开（公告）日：2009-06-11

  Pharmaceutical compositions containing a proanthocyanidin polymer composition which are useful for the treatment and prevention of secretory diarrhea are provided. The invention specifically relates to pharmaceutical formulations of a proanthocyanidin polymer composition which has been isolated from a Croton spp. or a Calophyllum spp. In particular, the invention relates to a formulation of a proanthocyanidin polymer composition which protects the composition from the effects of stomach acid after oral administration, particularly to those formulations which are enteric coated. The invention also relates to methods of producing a directly compressible proanthocyanidin polymer composition, as well as compositions containing the directly compressible proanthocyanidin polymer composition.
• US8574634B2
  申请人：——

  公开号：US8574634B2

  公开（公告）日：2013-11-05