N-naphthyl-N'-pentyluea | 101586-34-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: N-naphthyl-N'-pentyluea
• 英文别名: N-[1]naphthyl-N'-pentyl-urea；N-[1]Naphthyl-N'-pentyl-harnstoff；N-Pentyl-N'-naphth-1-yl-harnstoff；Pentyl-1-naphthylharnstoff；1-Naphthalen-1-yl-3-pentylurea
• CAS: 101586-34-9
• 化学式: C₁₆H₂₀N₂O
• 分子量: 256.348
• InChiKey: WWNZMPJZNYMTGY-UHFFFAOYSA-N

物化性质

• 沸点：
  396.4±15.0 °C(Predicted)
• 密度：
  1.107±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  41.1
• 氢给体数：
  2
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  N-[1]naphthyl-N'-pent-4-enyl-thiourea 在 乙醇 、 silver nitrate 、 铂 作用下， 生成 N-naphthyl-N'-pentyluea
  参考文献：
  名称：

  Kjaer; Jensen, Acta Chemica Scandinavica (1947), 1956, vol. 10, p. 1365,1368, 1371

  摘要：

  DOI：

文献信息

• Fluorescent sensor for α,ω-dicarboxylate anions
  作者：Minghua Mei、Shikang Wu

  DOI：10.1039/b007727p

  日期：——

  The synthesis and photophysical behavior of several naphthylurea derivatives used as chemosensors for detecting anionic species is reported. In particular, compound 3 shows a photoinduced electron transfer (PET) process. The photophysical properties of 3 upon the addition of dicarboxylate anions have been studied. Results show that fluorescence quenching of the naphthyl moiety and appearance of a new emission is induced by the formation of a complex. The obtained fluorescence and 1H-NMR data indicate that a 1:1 stoichiometry complex is formed between compound 3 and dicarboxylate anions through a hydrogen-bonding interaction. The selectivity of 3 for recognition of different dicarboxylates depends on the chain length of the anionic species.

  报告了几种用作阴离子物种检测化学传感器的萘脲衍生物的合成和光物理行为。其中，化合物 3 显示了光诱导电子转移（PET）过程。研究人员对 3 加入二羧酸阴离子后的光物理特性进行了研究。结果表明，萘基分子的荧光淬灭和新发射的出现是由复合物的形成诱导的。所获得的荧光和 1H-NMR 数据表明，化合物 3 与二羧酸阴离子之间通过氢键作用形成了 1:1 的配比复合物。化合物 3 识别不同二羧酸盐的选择性取决于阴离子物种的链长。
• NITROGENEOUS TRICYCLIC COMPOUND
  申请人：Asahi Kasei Pharma Corporation

  公开号：EP1829876A1

  公开（公告）日：2007-09-05

  A novel compound represented by the following formula (1) or a salt thereof [wherein R1, R5, R6, R7, and R8 represent hydrogen atom, a halogen atom, hydroxyl group, an alkyl group, an alkenyl group and the like; X1···X2 represents -CH(R2)-CH(R3)-, -CH(R2)-CH(R3)-CH(R4)-, -C(R2)=C(R3)-, or -C(R2)=C(R3)-CH(R4)- (R2, R3, and R4 represent hydrogen atom, or an alkyl group); A1, A11, A2, and A21 represent hydrogen atom, or an alkyl group; Y represents -CH(A3)-, -CH(A3)-C(A4)(A41)-, -CH(A3)-C(A4)(A41)-C(A5)(A51)-, or a single bond (A3, A4, A41, A5, and A51 represent hydrogen atom, or an alkyl group), and Z represents hydroxyl group, or -N(A6)(A61) (As represents hydrogen atom, or an alkyl group, and A61 represents hydrogen atom, an alkyl group, a substituted alkyl group and the like)], having an action of potently inhibiting phosphorylation of myosin regulatory light chain.

  由下式(1)代表的新型化合物或其盐[其中R1、R5、R6、R7和R8代表氢原子、卤素原子、羟基、烷基、烯基等；X1---X2代表-CH(R2)-CH(R3)-、-CH(R2)-CH(R3)-CH(R4)-、-C(R2)=C(R3)-或-C(R2)=C(R3)-CH(R4)-（R2、R3和R4代表氢原子或烷基）；A1、A11、A2和A21代表氢原子或烷基；Y 代表 -CH(A3)-、-CH(A3)-C(A4)(A41)-、-CH(A3)-C(A4)(A41)-C(A5)(A51)- 或单键（A3、A4、A41、A5 和 A51 代表氢原子或烷基），Z 代表羟基或 -N(A6)(A61) （As 代表氢原子、或烷基，A61 代表氢原子、烷基、取代的烷基等）]，具有有效抑制肌球蛋白调节轻链磷酸化的作用。
• Kjaer; Jensen, Acta Chemica Scandinavica (1947), 1956, vol. 10, p. 1365,1368, 1371
  作者：Kjaer、Jensen

  DOI：——

  日期：——