dibutylmethyltin hydride | 122749-52-4

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机过渡后金属化合物
• 英文名称: dibutylmethyltin hydride
• 英文别名: methyldibutyltin hydride；methyldibutylstannane；Dibutyl(methyl)stannane
• CAS: 122749-52-4
• 化学式: C₉H₂₂Sn
• 分子量: 248.984
• InChiKey: RKMPTVYKUIFHSW-UHFFFAOYSA-N

物化性质

• 沸点：
  224.7±9.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.44
• 重原子数：
  10
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  dibutylmethyltin hydride 、 methyl 2-[(S)-(4-methylphenyl)-[(4-methylphenyl)sulfonyl-prop-2-ynylamino]methyl]prop-2-enoate 在 三乙基硼 、 氧气 作用下， 以 正己烷 、 甲苯 为溶剂， 以16%的产率得到(3S,3aS)-methyl 5,5-dibutyl-3-(p-tolyl)-2-tosyl-1,2,3,3a,4,5-hexahydrostannolo[3,4-c]pyrrole-3a-carboxylate
  参考文献：
  名称：

  与锡原子相连的烷基的同质性比较

  摘要：

  AbstractDibutylmethyltin hydride and tert‐butyldibutyltin hydride were employed to examine radical cascade reaction of aza‐1,6‐enyne for the preliminary estimation of homofugality between alkyl groups by product distribution analysis. Use of either dibutylmethyltin hydride or tert‐butyldibutyltin hydride preferentially produced butylmethylstannolane, in which butyl group was mainly substituted by vinyl radical.

  DOI：

  10.1002/hc.21469
• 作为产物：
  描述：

  dibutylstannane 在 lithium diisopropyl amide 、 碘甲烷 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 以45%的产率得到dibutylmethyltin hydride
  参考文献：
  名称：

  通过新的（二有机锡）锂直接制备不对称的三有机锡氢化物

  摘要：

  Metalation of diorganostannanes R12SnH2 by lithium diisopropylamide afforded the corresponding (diorganostannyl)lithiums, R12SnHLi. Further reaction with halides led to unsymmetrically substituted alkyl-diorganostannanes, R12R2SnH. In situ stepwise dimetalation of diorganostannanes R12SnH2 gave the expected dialkylation products R12R22Sn with organic halides, aldehydes, and epoxides.

  DOI：

  10.1021/om00013a010

文献信息

• Direct Access to Unsymmetrical Tin Hydrides through (Hydridodiorganostannio)lithiums
  作者：Marie-Françoise Connil、Bernard Jousseaume、Michel Pereyre

  DOI：10.1021/om960444x

  日期：1996.10.15

  temperature. Further reaction with alkyl halides led to functional unsymmetrically substituted alkyldiorganostannanes, R12R2SnH. Tin hydrides with an ω-unsaturated substituent were stable at room temperature. With a 4-pentyl chain, they underwent a specific cyclization process, giving a stannacyclohexane under radical reaction conditions. A tin hydride with a tin−silicon bond could also be prepared.

  diorganostannanes的金属化- [R 1 2 SNH 2由二异丙基氨基锂，得到相应的（hydridodiorganostannio）lithiums，R 1 2 SnHLi，其分别稳定在低的温度。与卤代烷的进一步反应产生功能性不对称取代的烷基二有机锡烷，R 1 2 R 2 SnH。具有ω-不饱和取代基的氢化锡在室温下稳定。它们带有一个4-戊基链，经过特定的环化过程，在自由基反应条件下得到一个锡环己烷。也可以制备具有锡硅键的氢化锡。
• Comparison of homofugality among alkyl groups attached to tin atom
  作者：Akio Kamimura、Tatsuro Yoshinaga、Koichiro Miyazaki、Takuji Kawamoto

  DOI：10.1002/hc.21469

  日期：2018.12

  AbstractDibutylmethyltin hydride and tert‐butyldibutyltin hydride were employed to examine radical cascade reaction of aza‐1,6‐enyne for the preliminary estimation of homofugality between alkyl groups by product distribution analysis. Use of either dibutylmethyltin hydride or tert‐butyldibutyltin hydride preferentially produced butylmethylstannolane, in which butyl group was mainly substituted by vinyl radical.
• Straightforward preparation of unsymmetrical triorganotin hydrides through new (diorganostannyl)lithiums
  作者：Marie Francoise Connil、Bernard Jousseaume、Nicolas Noiret、Michel Pereyre

  DOI：10.1021/om00013a010

  日期：1994.1

  Metalation of diorganostannanes R12SnH2 by lithium diisopropylamide afforded the corresponding (diorganostannyl)lithiums, R12SnHLi. Further reaction with halides led to unsymmetrically substituted alkyl-diorganostannanes, R12R2SnH. In situ stepwise dimetalation of diorganostannanes R12SnH2 gave the expected dialkylation products R12R22Sn with organic halides, aldehydes, and epoxides.