2,5-bis<1-(1-hydroxyprop-2-ynyl)>thiophene | 186026-34-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻吩类
• 英文名称: 2,5-bis<1-(1-hydroxyprop-2-ynyl)>thiophene
• 英文别名: 2,5-di(1-hydroxyprop-2-yn-1-yl)thiophene；1,5-[H-C2-CH(OH)]2C4H2S；HCC(H)(OH)-2,5-(thiophene)-C(H)(OH)CCH；1-[5-(1-Hydroxyprop-2-ynyl)thiophen-2-yl]prop-2-yn-1-ol
• CAS: 186026-34-6
• 化学式: C₁₀H₈O₂S
• 分子量: 192.238
• InChiKey: MDADDKWMNWUDOO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  68.7
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  丙-2-炔-1-硫醇 、 2,5-bis<1-(1-hydroxyprop-2-ynyl)>thiophene 在 zinc(II) iodide 作用下， 以 二氯甲烷 为溶剂， 反应 0.5h， 以49%的产率得到2,5-bis<1-(prop-2-ynylthio)prop-2-ynyl>thiophene
  参考文献：
  名称：

  Synthesis of 3,4-bis[(methoxycarbonyl)methyl]thiophene and bis-, ter- and pentathiophenes with alternating 3,4-bis[(methoxycarbonyl)methyl]-substituted rings

  摘要：

  The synthesis of 3,4-bis[(methoxycarbonyl)methyl]thiophene and bis-, ter- and pentathiophenes, with alternating 3,4-bis(methoxycarbonyl)methyl-substituted rings, is reported, These new thiophene derivatives are possible precursors for the preparation of new conducting polymers useful as materials for electronics. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(98)01047-3
• 作为产物：
  描述：

  2,5-噻吩二甲醛 、 乙炔氢锂 生成 2,5-bis<1-(1-hydroxyprop-2-ynyl)>thiophene
  参考文献：
  名称：

  Synthesis of mixed bis(alkenylcarbene) ditungsten complexes by sequential activation of dialkynols

  摘要：

  The synthesis of new bis(alkenylcarbene) ditungsten complexes 2a-b, 5a and 6a has been achieved from W(CO)(5)(THF), via activation of the dialkynol derivatives a and b. The reaction of 5a with piperazine affords a dissymmetric bis(aminocarbene) complex 7a. (C) 1997 Elsevier Science S.A.

  DOI：

  10.1016/s0022-328x(97)00077-6

文献信息

• Functionalised alkenylcarbene metal complexes (M=Ru, W, Cr) by activation of propargyl alcohol derivatives
  作者：Karine Ulrich、Emmanuel Porhiel、Vincent Péron、Vincent Ferrand、Hubert Le Bozec

  DOI：10.1016/s0022-328x(00)00038-3

  日期：2000.4

  [Ru(η5-C5H5)(CO)(PPh3)(C(OMe)(CHCH-p-C6H4X)][BF4] (4a and 4d) are obtained from [Ru(η5-C5H5)(CO)(PPh3)(Cl)] (3) and propargyl alcohol derivatives a and d, respectively. Treatment of M(CO)5(THF) (M=W, Cr) with a and HCC(H)(OH)C4H2S(OH)(H)CCH (b) yields the monometallic complexes (CO)5MC(OMe)(C(OMe)(CHCHAr(OH)(H)CCH)] (5a) (M=W; Ar=C6H4), 5b (M=W; Ar=C4H2S), and 7a (M=Cr; Ar=C6H4)

  芳烃钌的反应（II）配合物的[Ru（η 6 -C 6我4 - [R 2）（PME 3）氯2 ]（1，R =甲基; 1 '，R = H）与炔丙醇衍生物HCC （H）（OH）（p -C 6 H ^ 4 X）（一个，X =HCC（H）（OH）; C ^，X = CHO; d，X =CHCH 2 ; ê，X = CHCHCHCH 2）和甲醇给出（甲氧基）-alkenylcarbene钌络合物的[Ru（η 6 -C 6我4 - [R 2）（PME3）（CL）（C（OME）（CHCH- p -C 6 H ^ 4 X）] [PF 6 ]（2A）和（2 ' ç - ë）。类似地，半夹心卡宾络合物的[Ru（η 5 -C 5 H ^ 5）（CO）（PPH 3）（C（OME）（CHCH- p -C 6 H ^ 4 X）] [BF 4 ]（图4a和4d中获得）从的[Ru（η 5 -C 5
• Novel carbon-rich binuclear ruthenium complexes with bis(allenylidene) bridges
  作者：Salaheddine Guesmi、Daniel Touchard、Pierre H. Dixneuf

  DOI：10.1039/cc9960002773

  日期：——

  Diruthenium(II) complexes with new bis(η1-allenylidene) bridges are produced by double activation of molecules containing two prop-2-yn-1-ol groups and offer two reversible redox processes.

  具有新型双（η1-丙炔基）桥的二铑（II）配合物通过对含有两个丙-2-炔-1-醇基团的分子进行双重活化而生成，并提供两个可逆的氧化还原过程。
• Carbon‐Rich Ruthenium Complexes Containing Bis(allenylidene) and Mixed Alkynyl−Allenylidene Bridges
  作者：Stéphane Rigaut、Johann Perruchon、Salaheddine Guesmi、Claire Fave、Daniel Touchard、Pierre H. Dixneuf

  DOI：10.1002/ejic.200400457

  日期：2005.2

  Complexes cis-[RuCl(dppe)2][X] (2a X = PF6, 2b X = CF3SO3) react with a variety of bis(propargylic) alcohols to selectively lead to mono-trans-[Cl(dppe)2Ru=C=C=C(R)−T−C(R)(OH)(C≡C−H)][X] (4) [R = H, Ph; T = m,p-(C6H4), 2,5-(thiophene), 5,5′-(2,2′-bithiophene), 5,5′′-(2,2′:5′2′′-terthiophene), −C≡C−] or bis(allenylidene) trans-[Cl(dppe)2Ru=C=C=C(R)−T−(R)C=C=C=RuCl(dppe)2][X]2 (5) complexes. New dimetallic

  配合物顺式-[RuCl(dppe)2][X] (2a X = PF6, 2b X = CF3SO3) 与多种双（炔）醇反应选择性地生成单反式-[Cl(dppe)2Ru=C =C=C(R)−T−C(R)(OH)(C≡C−H)][X] (4) [R = H, Ph; T = m,p-(C6H4), 2,5-(噻吩), 5,5'-(2,2'-联噻吩), 5,5''-(2,2':5'2''- terthiophene), -C≡C-] 或双（亚丙叉基）反式-[Cl(dppe)2Ru=C=C=C(R)-T-(R)C=C=C=RuCl(dppe)2][ X]2 (5) 络合物。新的双金属和三金属配合物含有混合炔基-亚丙叉基桥，反式-[Cl(dppe)2Ru-C≡C-p-(C6H4)-(Ph)C=C=C=RuCl(dppe)2][CF3SO3] ( 12) 和反式-[Cl(dppe)2Ru-C≡C-p
• Synthesis of mixed bis(alkenylcarbene) ditungsten complexes by sequential activation of dialkynols
  作者：Vincent Péron、Emmanuel Porhiel、Vincent Ferrand、Hubert Le Bozec

  DOI：10.1016/s0022-328x(97)00077-6

  日期：1997.7

  The synthesis of new bis(alkenylcarbene) ditungsten complexes 2a-b, 5a and 6a has been achieved from W(CO)(5)(THF), via activation of the dialkynol derivatives a and b. The reaction of 5a with piperazine affords a dissymmetric bis(aminocarbene) complex 7a. (C) 1997 Elsevier Science S.A.
• Synthesis of 3,4-bis[(methoxycarbonyl)methyl]thiophene and bis-, ter- and pentathiophenes with alternating 3,4-bis[(methoxycarbonyl)methyl]-substituted rings
  作者：Alessia Fazio、Bartolo Gabriele、Giuseppe Salerno、Silvia Destri

  DOI：10.1016/s0040-4020(98)01047-3

  日期：1999.1

  The synthesis of 3,4-bis[(methoxycarbonyl)methyl]thiophene and bis-, ter- and pentathiophenes, with alternating 3,4-bis(methoxycarbonyl)methyl-substituted rings, is reported, These new thiophene derivatives are possible precursors for the preparation of new conducting polymers useful as materials for electronics. (C) 1998 Elsevier Science Ltd. All rights reserved.