13-(4-methoxyphenyl)-5H-dibenzo[b,i]xanthene-5,7,12,14(13H)-tetraone | 1038917-60-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 萘并吡喃类
• 英文名称: 13-(4-methoxyphenyl)-5H-dibenzo[b,i]xanthene-5,7,12,14(13H)-tetraone
• 英文别名: 13-(4-Methoxyphenyl)-12h-dibenzo[b,i]xanthene-5,7,12,14(13h)-tetraone；13-(4-methoxyphenyl)-2-oxapentacyclo[12.8.0.03,12.05,10.016,21]docosa-1(14),3(12),5,7,9,16,18,20-octaene-4,11,15,22-tetrone
• CAS: 1038917-60-0
• 化学式: C₂₈H₁₆O₆
• 分子量: 448.431
• InChiKey: GPFAABBUMARACL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  34
• 可旋转键数：
  2
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  86.7
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  3,3′-[(4-methoxyphenyl)methylene]bis(2-hydroxynaphthalene-1,4-dione) 在 硫酸 作用下， 以 乙醇 为溶剂， 反应 0.42h， 以94%的产率得到13-(4-methoxyphenyl)-5H-dibenzo[b,i]xanthene-5,7,12,14(13H)-tetraone
  参考文献：
  名称：

  酸催化高效合成芳基-5H-二苯并[b，i] x吨-5,7,12,14-（13H）-四酮和3,3-（芳基亚甲基）双（2-羟基萘-1,4-二酮）及其抗氧化活性的体外评价

  摘要：

  简单有效地合成芳基5 H-二苯并[ b，i ]蒽并-5,7,12,14-（13 H）-四酮和3,3-（芳基亚甲基）双（2-羟基萘-1,4） -二酮）是在极温和的条件下，使用催化量的H 2 SO 4或在酸性离子液体1-丁基-3-甲基咪唑鎓硫酸氢盐存在下，通过芳族醛与2-羟基-1,4-萘醌的缩合反应制得的。可以回收利用，据报道。已检查了合成化合物对稳定的自由基2,2-二苯基-1-吡啶并肼基（DPPH）的清除自由基的能力，发现化合物2可有效清除DPPH自由基。

  DOI：

  10.1002/jhet.1871

文献信息

• Graphene Oxide Incorporated Strontium Nanoparticles as a Highly Efficient and Green Acid Catalyst for One-Pot Synthesis of Tetramethyl-9-aryl-hexahydroxanthenes and 13-Aryl-5H-dibenzo[b,i]xanthene-5,7,12,14(13H)-tetraones Under Solvent-Free Conditions
  作者：Seyyed Rasul Mousavi、Hamid Rashidi Nodeh、Elham Zamiri Afshari、Alireza Foroumadi

  DOI：10.1007/s10562-019-02675-0

  日期：2019.4.15

  applying graphene oxide/strontium as a nanocatalyst for xanthene derivatives synthesis. The key potential benefits of the present method are including high yields, short reaction time, easy workup, recyclability of catalyst and ability to tolerate a variety of functional groups which gives economical as well as ecological rewards. The nanocatalyst easily separated from the reaction mixture easily by

  合成了一种高效、廉价且可回收的氧化石墨烯/锶纳米催化剂，并将其应用于芳香醛和二甲酮/洛森的伪三组分一锅环缩合反应中，得到相应的 3,3,6,6-四甲基-9-芳基-3,4,5,6,7,9-六氢-1H-呫吨-1,8(2H)-二酮和13-芳基-5H-二苯并[b,i]呫吨-5,7,12,14( 13H)-四酮在无溶剂条件下高产率。据我们所知，目前还没有关于将氧化石墨烯/锶用作合成呫吨衍生物的纳米催化剂的文献报道。本方法的主要潜在优势包括高产率、反应时间短、易于后处理、催化剂的可回收性以及耐受各种官能团的能力，从而带来经济和生态回报。
• A simple procedure for the synthesis of benzoxanthene derivatives under microwave irradiation conditions
  作者：Yan Chen、Shanshan Wu、Shujiang Tu、Chunmei Li、Feng Shi

  DOI：10.1002/jhet.5570450345

  日期：2008.5

  A rapid and efficient method is developed to synthesize a series of benzoxanthene derivatives by the reaction of aldehydes and 2-hydroxynaphthalene-1,4-dione in mixed solvent of acetic acid and ethylene glycol under microwave irradiation. The method has the advantages of short synthetic route, operational simplicity and higher yields (70%∼85%).

  开发了一种快速有效的方法，通过在微波和乙酸和乙二醇的混合溶剂中，醛类与2-羟基萘-1,4-二酮反应，合成一系列苯并氧杂蒽衍生物。该方法具有合成路线短，操作简便和产率高（70％〜85％）的优点。
• Catalytic application of a nano-molten salt catalyst in the synthesis of biological naphthoquinone-based compounds
  作者：Meysam Yarie、Mohammad Ali Zolfigol、Saeed Babaee、Saeed Baghery、Diego A. Alonso、Abbas Khoshnood

  DOI：10.1007/s11164-018-3264-9

  日期：2018.4

  Abstract In this investigation, a new application of 1 H -imidazol-3-ium tricyanomethanide catalyst was explored. The catalyst presented a robust catalytic applicability for the preparation of naphthoquinone-based compounds under mild and green reaction conditions. A wide range of aromatic aldehydes were able to react with 2-hydroxynaphthalene-1,4-dione and 3-methyl-1-phenyl-1 H -pyrazol-5(4 H )-one

  摘要 在本研究中，探索了1 H- 咪唑-3-三氰基氨基甲烷催化剂的新应用 。该催化剂在温和和绿色的反应条件下，对于制备基于萘醌的化合物具有很强的催化适用性。多种芳族醛能够与2-羟基萘-1,4-二酮和3-甲基-1-苯基-1 H- 吡唑-5（4 H ）-一或丙二腈反应，得到所需的萘醌基分子在短时间内以高至优异的产率。 图形摘要 用2-羟基萘-1,4-二酮（henna）和3-甲基-1-苯基-1 H- 吡唑-5（4 H ）处理了各种芳香醛 或丙二腈可在短反应时间内提供所需的基于指甲花的目标分子，并具有良好或极好的收率。
• Immobilized copper-layered nickel ferrite on acid-activated montmorillonite, [(NiFe₂O₄@Cu)(H⁺-Mont)], as a superior magnetic nanocatalyst for the green synthesis of xanthene derivatives
  作者：Behzad Zeynizadeh、Soleiman Rahmani

  DOI：10.1039/c9ra04320a

  日期：——

  Moreover, through the activation of montmorillonite K10 (Mont K10) with HCl (4 M) under controlled conditions, the H+-Mont constituent was prepared. The nanostructured NiFe2O4@Cu was then intercalated within the interlayers and on the external surface of the H+-Mont constituent to afford the novel magnetic nanocomposite (NiFe2O4@Cu)(H+-Mont). The prepared clay nanocomposite was characterized using FTIR spectroscopy

  在这项研究中，研究了铜层状镍铁氧体在酸活化蒙脱石（H + -Mont）的表面和空腔中的固定化。在此背景下，制备了作为主磁芯的NiFe 2 O 4磁性纳米颗粒（MNP） 。接着，通过硼氢化钠还原Cu 2+离子，将Cu 0纳米颗粒固定在NiFe 2 O 4 的纳米核表面，得到组成NiFe 2 O 4 @Cu MNPs。此外，通过在受控条件下用 HCl (4 M) 活化蒙脱石 K10 (Mont K10)，H +-准备了Mont成分。然后将纳米结构的 NiFe 2 O 4 @Cu 插入中间层内和 H + -Mont 成分的外表面上，以提供新型磁性纳米复合材料 (NiFe 2 O 4 @Cu)(H + -Mont)。使用 FTIR 光谱、SEM、EDX、XRD、VSM 和 BET 分析对制备的粘土纳米复合材料进行了表征。所得结果表明，通过酸活化，Mont K10 的叠片结构被剥离成微小的片段，导致
• N-Sulfonic acid poly(4-vinylpyridinium) hydrogen sulfate as an efficient and reusable solid acid catalyst for one-pot synthesis of xanthene derivatives in dry media under ultrasound irradiation
  作者：Nader Ghaffari Khaligh、Farhad Shirini

  DOI：10.1016/j.ultsonch.2014.06.020

  日期：2015.1

  N-Sulfonic acid poly(4-vinylpyridinium) hydrogen sulfate catalyzed efficiently the synthesis of xanthene derivatives under ultrasonic irradiation at room temperature, which has prompted various concerns involving cost and environmental persistence. This methodology shows the effect of presence of anion hydrogen sulfate as an important and effective factor on the promotion of the one-pot multi-components and condensation reactions. The catalyst can be recovered by simple filtration and used for several times without a significant loss of catalytic activity. (C) 2014 Elsevier B.V. All rights reserved.