diethyl hex-3-yne-2,5-diyl biscarbonate | 1094215-61-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机碳酸及其衍生物
• 英文名称: diethyl hex-3-yne-2,5-diyl biscarbonate
• 英文别名: 5-Ethoxycarbonyloxyhex-3-yn-2-yl ethyl carbonate
• CAS: 1094215-61-8
• 化学式: C₁₂H₁₈O₆
• 分子量: 258.271
• InChiKey: FBMQYOCWIQYVHP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  18
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  71.1
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  正癸烯 、 diethyl hex-3-yne-2,5-diyl biscarbonate 在 RuCl2(1,3-dimesityl-imidazolidin-2-yl)(PCy3)(=CHPh) 作用下， 以 碳酸二甲酯 为溶剂， 反应 2.0h， 生成 diethyl (3-methylene-4-nonylidenehexane-2,5-diyl) bis(carbonate)
  参考文献：
  名称：

  涉及Enyne跨置换的不饱和脂肪酯的首次转化

  摘要：

  Abstractmagnified imageThe ruthenium‐catalysed enyne cross‐metathesis of several alkyne derivatives with terminal olefins was performed. These reactions were efficiently achieved under mild conditions in dimethyl carbonate, an eco‐friendly solvent. A unique one‐pot reaction based on an ethenolysis step followed by an enyne cross‐metathesis allowed the efficient transformation of renewable unsaturated fatty esters into valuable conjugated 1,3‐dienes of interest for further transformations.

  DOI：

  10.1002/adsc.200800726

文献信息

• Ruthenium-Catalyzed Synthesis of Functionalized 1,3-Dienes
  作者：Mathieu Achard、Nolwenn Derrien、Hui-Jun Zhang、Bernard Demerseman、Christian Bruneau

  DOI：10.1021/ol8023488

  日期：2009.1.1

  Functionalized 1,3-diene derivatives have been prepared by regioselective allylation of various nucleophiles with 1,3-dienic carbonates In the presence of a (N,O-carboxylate) allylruthenium precatalyst.
• First Transformation of Unsaturated Fatty Esters Involving Enyne Cross-Metathesis
  作者：Virginie Le Ravalec、Cédric Fischmeister、Christian Bruneau

  DOI：10.1002/adsc.200800726

  日期：2009.5

  Abstractmagnified imageThe ruthenium‐catalysed enyne cross‐metathesis of several alkyne derivatives with terminal olefins was performed. These reactions were efficiently achieved under mild conditions in dimethyl carbonate, an eco‐friendly solvent. A unique one‐pot reaction based on an ethenolysis step followed by an enyne cross‐metathesis allowed the efficient transformation of renewable unsaturated fatty esters into valuable conjugated 1,3‐dienes of interest for further transformations.