4-methyl-2-undecyl-2-oxazoline | 117815-18-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑啉类
• 英文名称: 4-methyl-2-undecyl-2-oxazoline
• 英文别名: 4-methyl-2-undecyl-4,5-dihydro-1,3-oxazole
• CAS: 117815-18-6
• 化学式: C₁₅H₂₉NO
• 分子量: 239.401
• InChiKey: VMOSGQRKWSAOGW-UHFFFAOYSA-N

物化性质

• 沸点：
  115-117 °C(Press: 1 Torr)
• 密度：
  0.93±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  17
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  21.6
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  十二腈 、 DL-氨基丙醇 在 cadmium(II) acetate dihydrate 作用下， 以 正丁醇 为溶剂， 115.0~117.0 ℃ 、26.66 kPa 条件下， 以13.2 g (92%) of product was obtained on distillation at 115°-117° C./1-1.5 mm Hg的产率得到4-methyl-2-undecyl-2-oxazoline
  参考文献：
  名称：

  Compositions and method comprising heterocyclic compounds containing two

  摘要：

  一种增强生理活性制剂经皮肤和黏膜吸收的方法和组合物，用于局部或全身性使用的经皮装置或配方，包括治疗有效量的药物活性剂和化合物I的非毒性有效量的渗透增强剂： 其中R是具有1至19个碳原子的饱和或不饱和的直链或支链、环状或非环状的烃基、烷氧基烷基、卤代烷基、特别是三氟甲基、烷氧基、氨基、烷基氨基和酰胺基；R'和R"是氢、烷基、三氟甲基、烷氧基烷基、氨基烷基、烷基和酰胺基烷基、羧基、羧酸酯、羟基烷基或其较低烷基酯；X是O或NR1，其中R1是氢、烷基、烯基、烷氧基烷基、羧基烷氧基烷基、氨基烷基、烷基和酰胺基烷基、羟基烷基或羟基烷氧基烷基和其较低烷基酯；n为2或3。

  公开号：

  US05030629A1

文献信息

• Purified polyoxypropylene fatty acid isopropanolamide surfactants, production thereof and detergent compositions containing the surfactants
  申请人：——

  公开号：US20030176311A1

  公开（公告）日：2003-09-18

  A refined product of a polyoxypropylene fatty acid isopropanolamide surfactant, having a high stability in storage and a very small change in smell thereof, is obtained by heat-treating an addition-reaction mixture prepared from a compound of the formula (III) and propylene oxide in a molar amount of 0.5 to 10 times that of the compound of the formula (III), and containing the target compound of the formula (I) and an oxazoline compound of the formula (II) produced as a by-product with water or an alkaline aqueous solution at 50 to 100° C., to hydrolyze the oxyazoline compound and to control the content of the oxyazoline compound to 0.1% by mass or less; and a detergent composition containing the refined product in a content of 1 to 50% by mass, exhibits enhanced thickening, foaming, emulsifying, dispersing and dissolving properties. R 1 —CONH—CH 2 CH(CH 3 ) (X) n OH  (I) 1 R 1 —CONH—CH 2 CH(CH 3 )—OH  (III) [R 1 =C 1 -C 19 alkyl or alkenyl group, X=oxypropylene group, n=average number of addition-reacted X groups of 0.5 to 10]

  一种聚氧丙烯脂肪酸异丙醇酰胺表面活性剂的精制产品，具有很高的贮存稳定性和极小的气味变化，是通过热处理由式(III)化合物和环氧丙烷制备的加成反应混合物得到的，该混合物的摩尔量是式(III)化合物的 0.5至10倍的式(III)化合物制备的加成反应混合物，其中含有式(I)的目标化合物和作为副产物生成的式(II)的噁唑啉化合物、使噁唑啉化合物水解，并将噁唑啉化合物的含量控制在 0.1%（以质量计）或更低；含有该精制产品的洗涤剂组合物，其含量为 1 至 50%（以质量计），具有增强的增稠、发泡、乳化、分散和溶解特性。 R 1 -CONH-CH 2 CH(CH 3 ) (X) n OH (I) 1 R 1 -CONH-CH 2 CH(CH 3 ）-OH (III) [R 1 等于;C 1 -C 19 烷基或烯基，X&等于;氧丙烯基，n&等于;加成反应的 X 基团的平均数量为 0.5 至 10&rsqb；
• PURIFIED POLYOXYPROPYLENE FATTY ACID ISOPROPANOLAMIDE SURFACTANTS, PRODUCTION THEREOF AND DETERGENT COMPOSITIONS CONTAINING THE SURFACTANTS
  申请人：Kawaken Fine Chemicals Co., Ltd.

  公开号：EP1298123B1

  公开（公告）日：2007-09-05
• HETEROCYCLIC COMPOUNDS FOR TRANSDERMAL USE
  申请人：RAJADHYAKSHA, Vithal J.

  公开号：EP0296199A1

  公开（公告）日：1988-12-28
• Process for producing a refined product of polyoxyproylene fatty acid isopropanolamide surfactant
  申请人：Ito Toyofumi

  公开号：US20050187135A1

  公开（公告）日：2005-08-25

  A refined product of a polyoxypropylene fatty acid isopropanolamide surfactant, having a high stability in storage and a very small change in smell thereof, is obtained by heat-treating an addition-reaction mixture prepared from a compound of the formula (III) and propylene oxide in a molar amount of 0.5 to 10 times that of the compound of the formula (III), and containing the target compound of the formula (I) and an oxazoline compound of the formula (II) produced as a by-product with water or an alkaline aqueous solution at 50 to 100° C., to hydrolyze the oxyazoline compound and to control the content of the oxyazoline compound to 0.1% by mass or less; and a detergent composition containing the refined product in a content of 1 to 50% by mass, exhibits enhanced thickening, foaming, emulsifying, dispersing and dissolving properties. [R 1 =C 1 -C 19 alkyl or alkenyl group, X=oxypropylene group, n=average number of addition-reacted X groups of 0.5 to 10]
• US4876249A
  申请人：——

  公开号：US4876249A

  公开（公告）日：1989-10-24