bis(2-N,N-dimethylaminoethyl) carbonate | 3030-45-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机碳酸及其衍生物
• 英文名称: bis(2-N,N-dimethylaminoethyl) carbonate
• 英文别名: bis-(2-(dimethyl amino)ethyl) carbonate；DAEC；carbonic acid bis-(2-dimethylamino-ethyl ester)；Kohlensaeure-bis-(2-dimethylamino-aethylester)；bis[2-(N,N-dimethylamino)ethyl] carbonate；bis[2-(N,N-dimethylamino)ethyl]carbonate；Bis(2-(dimethylamino)ethyl) carbonate；bis[2-(dimethylamino)ethyl] carbonate
• CAS: 3030-45-3
• 化学式: C₉H₂₀N₂O₃
• 分子量: 204.269
• InChiKey: VRJRVIUWJWYDMT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  14
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  42
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  溴甲烷 、 bis(2-N,N-dimethylaminoethyl) carbonate 在 氯仿 作用下， 生成 carbonic acid bis-(2-trimethylammonio-ethyl ester); dibromide
  参考文献：
  名称：

  Bis-aminoalkyl carbonate derivatives

  摘要：

  公开号：

  US02691017A1
• 作为产物：
  描述：

  N,N-二甲基乙醇胺 、 碳酸二乙酯 在 potassium carbonate 作用下， 生成 bis(2-N,N-dimethylaminoethyl) carbonate
  参考文献：
  名称：

  Bis-aminoalkyl carbonate derivatives

  摘要：

  公开号：

  US02691017A1

文献信息

• Methods for treatment of dermatological conditions
  申请人：Wang Bing

  公开号：US20050032751A1

  公开（公告）日：2005-02-10

  A method of reducing the appearance of skin conditions associated with loss of skin tightness, skin firmness, or dark circles under the eyes with topical compositions comprising compounds of any of the Formulae I or Ia as described herein, is disclosed.

  本文揭示了一种通过含有本文所述的任何Formulae I或Ia化合物的局部组合物来减少与皮肤松弛、皮肤紧致度或眼部黑眼圈相关的皮肤状况的方法。
• Synthesis of dimethyl carbonate (DMC) based biodegradable nitrogen mustard ionic carbonate (NMIC) nanoparticles
  作者：P. Thyriyalakshmi、K. V. Radha

  DOI：10.1039/c4ra13290d

  日期：——

  Nitrogen mustard ionic carbonate with stable carbonate moiety was synthesized and cross-linked with the biopolymer chitosan. Subsequently, nanoparticles of cross linked chitosan were prepared for wound healing application.

  氮芥离子碳酸盐与稳定碳酸盐基团结合，并与生物聚合物壳聚糖进行交联。随后，制备了交联壳聚糖的纳米粒子，用于伤口愈合应用。
• Processes for the preparation of aminoethers
  申请人：Union Carbide Chemicals & Plastics Technology Corporation

  公开号：US05214142A1

  公开（公告）日：1993-05-25

  A process for preparing aminoethers, particularly bis[2-(N,N-dialkylamino)alkyl]ethers, which comprises contacting a carboxylated aminoether with a metal oxide catalyst under conditions effective to produce the aminoether. Many of these aminoethers are useful as catalysts in the production of polyurethanes, especially cellular polyurethanes.

  一种制备氨基醚的方法，特别是双[2-(N,N-二烷基氨基)烷基]醚，包括将羧化氨基醚与金属氧化物催化剂接触，在有效条件下产生氨基醚。这些氨基醚中的许多在生产聚氨酯，特别是细胞聚氨酯的催化剂中非常有用。
• Aminocarbonate compounds and their use as catalysts
  申请人：Air Products and Chemicals, Inc.

  公开号：US05686643A1

  公开（公告）日：1997-11-11

  Diaminocarbonate compounds are disclosed which are particularly suitable as low-odor catalysts for the production of solid or cellular urethane polymers and/or urea polymers. The compounds are obtainable by reacting amino alcohols with alkyl carbonates.

  本发明揭示了一种二氨基碳酸盐化合物，特别适用于生产固体或泡沫脲聚合物和/或尿素聚合物的低气味催化剂。该化合物可通过将氨基醇与烷基碳酸酯反应得到。
• Process for the preparation of tertiary aminocarbonates and aminoethers
  申请人：OSi Specialties, Inc.

  公开号：US05563288A1

  公开（公告）日：1996-10-08

  The invention relates to processes for producing di-(tertiary aminoalkyl) carbonate including the step of reacting a tertiary alkanolamine with methyl alkyl carbonate in the presence of a transesterification catalyst to form tertiary aminoalkyl alkyl carbonate, wherein some of the tertiary alkanolamine reacts with the tertiary aminoalkyl alkyl carbonate to form di-(tertiary aminoalkyl) carbonate. The invention also relates to processes for producing di-(tertiary aminoalkyl) carbonate including the steps of (i) reacting dimethyl carbonate with an alcohol in the presence of a transesterification catalyst to form a methyl alkyl carbonate, and (ii) reacting a tertiary alkanolamine with the methyl alkyl carbonate formed in step i) in the presence of a transesterification catalyst to form tertiary aminoalkyl alkyl carbonate, wherein some of the tertiary alkanolamine reacts with the tertiary aminoalkyl alkyl carbonate to form di-(tertiary aminoalkyl) carbonate.

  本发明涉及制备二-(三级氨基烷基)碳酸酯的过程，包括以下步骤：在转酯化催化剂的存在下，将三级醇胺与甲基烷基碳酸酯反应，形成三级氨基烷基烷基碳酸酯，其中部分三级醇胺与三级氨基烷基烷基碳酸酯反应，形成二-(三级氨基烷基)碳酸酯。本发明还涉及制备二-(三级氨基烷基)碳酸酯的过程，包括以下步骤：(i)在转酯化催化剂的存在下，将二甲基碳酸酯与醇反应，形成甲基烷基碳酸酯；(ii)在转酯化催化剂的存在下，将三级醇胺与步骤(i)中形成的甲基烷基碳酸酯反应，形成三级氨基烷基烷基碳酸酯，其中部分三级醇胺与三级氨基烷基烷基碳酸酯反应，形成二-(三级氨基烷基)碳酸酯。