Novel 10, 10'-substituted-9,9'-biacridine luminescent molecules and their preparation
申请人:PIERCE CHEMICAL COMPANY
公开号:EP1026156A2
公开(公告)日:2000-08-09
Novel symmetrical and asymmetrical 10,10'-substituted-9,9'-biacridines and the synthesis of such symmetrical and asymmetrical 10,10'-substituted-9,9'-biacridine molecules and their derivatives is disclosed. These molecules are shown to produce light by chemiluminescence in the presence of signal solutions. These symmetrical or asymmetrical 10,10'-substituted-9,9'-biacridines are used alone or attached to haptens or macromolecules and are utilized as labels in the preparation of chemiluminescent, homogeneous or heterogeneous assays. They are also used in conjunction with other chemiluminescent label molecules to produce multiple analyte chemiluminescent assays.
本发明公开了新颖的对称和不对称 10,10'-取代-9,9'-联吖啶以及这种对称和不对称 10,10'-取代-9,9'-联吖啶分子及其衍生物的合成方法。这些分子在有信号溶液的情况下通过化学发光产生光。这些对称或不对称的 10,10'-取代-9,9'-联吖啶可单独使用,也可附在触媒或大分子上使用,并在制备化学发光、均相或异相检测试剂时用作标记。它们还可与其他化学发光标签分子结合使用,以产生多分析物化学发光检测。