1,2-bis(m-methoxycarbonylphenyl)ethane | 96841-94-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 1,2-bis(m-methoxycarbonylphenyl)ethane
• 英文别名: 3,3'-Dicarbomethoxy-bibenzyl；bibenzyl-3,3'-dicarboxylic acid dimethyl ester；Bibenzyl-3,3'-dicarbonsaeure-dimethylester；Methyl 3-[2-(3-methoxycarbonylphenyl)ethyl]benzoate
• CAS: 96841-94-0
• 化学式: C₁₈H₁₈O₄
• 分子量: 298.339
• InChiKey: GNKWTWFGKVDMPC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,2-bis(m-methoxycarbonylphenyl)ethane 在 lithium aluminium tetrahydride 作用下， 生成 3,3'-bis(hydroxymethyl)diphenylethane
  参考文献：
  名称：

  Syntheses of 4,12-Dimethyl[2.2]metacyclophane

  摘要：

  DOI：

  10.1021/ja01465a044
• 作为产物：
  描述：

  3-溴苄溴 在 吡啶 、 硫酸 作用下， 生成 1,2-bis(m-methoxycarbonylphenyl)ethane
  参考文献：
  名称：

  Syntheses of 4,12-Dimethyl[2.2]metacyclophane

  摘要：

  DOI：

  10.1021/ja01465a044

文献信息

• Reactions of benzyltriphenylphosphonium salts under photoredox catalysis
  作者：Andrew M. Boldt、Sidney I. Dickinson、Jonathan R. Ramirez、Anna M. Benz-Weeden、David S. Wilson、Susan M. Stevenson

  DOI：10.1039/d1ob01570b

  日期：——

  The development of benzyltriphenylphosphonium salts as alkyl radical precursors using photoredox catalysis is described. Depending on substituents, the benzylic radicals may couple to form C–C bonds or abstract a hydrogen atom to form C–H bonds. A natural product, brittonin A, was also synthesized using this method.

  描述了使用光氧化还原催化开发作为烷基自由基前体的苄基三苯基鏻盐。根据取代基的不同，苄基可以偶联形成 C-C 键或夺取氢原子以形成 C-H 键。使用这种方法还合成了一种天然产物 Brittonin A。
• REDUCTIVE COUPLING OF BENZYL HALIDES USING NICKEL(0)-COMPLEX GENERATED IN SITU IN THE PRESENCE OF TETRAETHYLAMMONIUM IODIDE, A SIMPLE AND CONVENIENT SYNTHESIS OF BIBENZYLS
  作者：Masahiko Iyoda、Masahiro Sakaitan、Hiroki Otsuka、Masaji Oda

  DOI：10.1246/cl.1985.127

  日期：1985.1.5

  Zerovalent nickel complex generated in situ by reduction of NiBr2(PPh3)2 with zinc powder in the presence of Et4NI was found to be an effective catalyst for homo-coupling of benzyl halides. The catalytic reactions proceeded smoothly in various solvents under mild conditions to afford dehalogenative-coupling products in good to high yields.

  发现在 Et4NI 存在下用锌粉还原 NiBr2(PPh3)2 原位生成的零价镍配合物是苄基卤化物均偶联的有效催化剂。催化反应在温和条件下在各种溶剂中顺利进行，以良好到高产率提供脱卤偶联产物。
• MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME
  申请人：TABATA Masayoshi

  公开号：US20110224343A1

  公开（公告）日：2011-09-15

  The present invention provides a modifier for aromatic polyesters which enhances the melt fluidity of aromatic polyesters without a significant decrease in the heat resistance of the aromatic polyesters, and an aromatic polyester resin composition including the modifier for aromatic polyesters. The present invention relates to a modifier for aromatic polyesters comprising polyhydric phenol residues and residues of aromatic polycarboxylic acid, acid halide or acid anhydride thereof, and the modifier comprises a material having a structure composed of a first residue selected from the group consisting of divalent residues represented by Formula (I): —Ar—W 1 x —Ar— and by Formula (II): —Ar—, the first residues being bonded to two identical or different second residues selected from the group consisting of monovalent residues represented by Formula (III): and monovalent residues represented by Formula (IV): —O—C(O)—R 7 —.

  本发明提供了一种用于芳香族聚酯的改性剂，可以增强芳香族聚酯的熔融流动性，而不明显降低芳香族聚酯的耐热性，以及包括该改性剂的芳香族聚酯树脂组合物。本发明涉及一种用于芳香族聚酯的改性剂，包括多羟基酚残基和芳香族多羧酸、酸卤或其酸酐残基，该改性剂包括具有以下结构的材料：第一残基，选择自由式(I)所代表的二价残基：—Ar—W1x—Ar—和自由式(II)所代表的：—Ar—，第一残基与选择自由式(III)所代表的单价残基：和自由式(IV)所代表的单价残基：—O—C(O)—R7—的两个相同或不同的第二残基结合。
• 1,2-Ethylene-3,3-bis(4′,4′′-dimethoxytrityl Chloride) (E-DMT): Synthesis and Applications of a Novel Protecting Reagent
  作者：Yogesh S. Sanghvi、Natsuhisa Oka、Emmanuel A. Theodorakis

  DOI：10.1055/s-2004-820033

  日期：——

  1,2-Ethylene-3,3-bis(4′,4′′-dimethoxytrityl chloride), (E-DMT) was developed as a novel, bifunctional protecting reagent. This new compound was found to have a potential as a multipurpose acid-labile protecting reagent which can afford a 5′,5′-tritylthymidine dimer and a unique 5′,3′-cyclic protected thymidine derivative in modest to good yields.

  1,2-乙烯-3,3-双（4′,4′′-二甲氧基三苯甲基氯）（E-DMT）作为一种新型双功能保护试剂被开发出来。研究发现，这种新化合物具有作为多用途酸亲和性保护试剂的潜力，能以适度到良好的产率获得 5′,5′-三苯甲基胸苷二聚物和独特的 5′,3′-环保护胸苷衍生物。
• Hydrodeoxygenative Coupling and Transformation of Aldehydes at a N₂-Derived Tetranuclear Titanium Imide/Hydride Framework
  作者：Yat-Ming So、Ching Tat To、Murali Mohan Guru、Takanori Shima、Zhaomin Hou

  DOI：10.1021/jacs.3c05525

  日期：2023.8.2

  transformations in organic synthesis. Herein, we report an unprecedented hydrodeoxygenative coupling of aromatic aldehydes to form bibenzyls by a N2-derived tetranuclear titanium imide/hydride complex [(Cp′Ti)4(μ3-NH)2(μ-H)4] (1; Cp′ = C5Me4SiMe3). Further reactions with the corresponding aldehydes under air afford hydrobenzamides together with a titanium oxo complex. Both hydride and imide ligands play an important

  通过两种有机组分的偶联形成碳-碳键是有机合成中最重要的化学转化之一。在此，我们报道了一种前所未有的芳香醛加氢脱氧偶联反应，通过N 2衍生的四核钛亚胺/氢化物配合物[(Cp'Ti) 4 (μ 3 -NH) 2 (μ-H) 4 ] ( 1 ; Cp′ = C 5 Me 4 SiMe 3 )。在空气下与相应的醛进一步反应，得到氢苯甲酰胺以及钛氧络合物。氢化物和酰亚胺配体对于还原偶联、氢化过程以及N 2衍生的酰亚胺单元的官能化都起着重要作用，而无需牺牲试剂。这些结果表明，四核钛酰亚胺/氢化物骨架不仅适用于N 2活化和功能化，而且还为使用羰基化合物形成C-C键提供了新的平台。