4-(Chlorosulfinyloxymethyl)-2-oxo-1,3-dioxolane | 1263905-66-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机碳酸及其衍生物
• 英文名称: 4-(Chlorosulfinyloxymethyl)-2-oxo-1,3-dioxolane
• 英文别名: 4-(chlorosulfinyloxymethyl)-2-oxo-1,3-dioxolane
• CAS: 1263905-66-3
• 化学式: C₄H₅ClO₅S
• 分子量: 200.6
• InChiKey: ULEUPDMJQXJQNN-UHFFFAOYSA-N

物化性质

• 熔点：
  110 °C (decomp)
• 沸点：
  446.2±37.0 °C(Predicted)
• 密度：
  1.73 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  81
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  4-(Chlorosulfinyloxymethyl)-2-oxo-1,3-dioxolane 在 18-冠醚-6 、 potassium chloride 作用下， 以 甲苯 为溶剂， 反应 3.0h， 生成 4-(氯甲基)-1,3-二氧戊环-2-酮
  参考文献：
  名称：

  Converting wastes into added value products: from glycerol to glycerol carbonate, glycidol and epichlorohydrin using environmentally friendly synthetic routes

  摘要：

  Glycerol carbonate, synthesised via a non-phosgene route using glycerol and CO(2) or urea in presence of a heterogeneous catalyst, was efficiently converted into a series of derivatives through the functionalization of the -OH moiety, using high yield, high selectivity synthetic routes not affecting the carbonate functionality. So, for example, glycerol carbonate was converted into epichlorohydrin, a product that has a large industrial application, under very mild conditions, using a two-step reaction with a 98% yield and 100% selectivity. The high yield and mild reaction conditions (very often close to the ambient conditions) make the environmentally friendly synthetic approach described in this work of potential applicative interest. All compounds prepared were fully characterized. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2010.11.070
• 作为产物：
  描述：

  羟甲基二氧杂戊环酮 在 氯化亚砜 作用下， 反应 1.0h， 以99.1%的产率得到4-(Chlorosulfinyloxymethyl)-2-oxo-1,3-dioxolane
  参考文献：
  名称：

  Converting wastes into added value products: from glycerol to glycerol carbonate, glycidol and epichlorohydrin using environmentally friendly synthetic routes

  摘要：

  Glycerol carbonate, synthesised via a non-phosgene route using glycerol and CO(2) or urea in presence of a heterogeneous catalyst, was efficiently converted into a series of derivatives through the functionalization of the -OH moiety, using high yield, high selectivity synthetic routes not affecting the carbonate functionality. So, for example, glycerol carbonate was converted into epichlorohydrin, a product that has a large industrial application, under very mild conditions, using a two-step reaction with a 98% yield and 100% selectivity. The high yield and mild reaction conditions (very often close to the ambient conditions) make the environmentally friendly synthetic approach described in this work of potential applicative interest. All compounds prepared were fully characterized. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2010.11.070

文献信息

• Converting wastes into added value products: from glycerol to glycerol carbonate, glycidol and epichlorohydrin using environmentally friendly synthetic routes
  作者：Angela Dibenedetto、Antonella Angelini、Michele Aresta、Jayashree Ethiraj、Carlo Fragale、Francesco Nocito

  DOI：10.1016/j.tet.2010.11.070

  日期：2011.2

  Glycerol carbonate, synthesised via a non-phosgene route using glycerol and CO(2) or urea in presence of a heterogeneous catalyst, was efficiently converted into a series of derivatives through the functionalization of the -OH moiety, using high yield, high selectivity synthetic routes not affecting the carbonate functionality. So, for example, glycerol carbonate was converted into epichlorohydrin, a product that has a large industrial application, under very mild conditions, using a two-step reaction with a 98% yield and 100% selectivity. The high yield and mild reaction conditions (very often close to the ambient conditions) make the environmentally friendly synthetic approach described in this work of potential applicative interest. All compounds prepared were fully characterized. (C) 2010 Elsevier Ltd. All rights reserved.