3-Ethoxy-2-methylidene-4-(2-methylpropyl)oxetane | 185449-73-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧杂环丁烷
• 英文名称: 3-Ethoxy-2-methylidene-4-(2-methylpropyl)oxetane
• 英文别名: 3-ethoxy-2-methylidene-4-(2-methylpropyl)oxetane
• CAS: 185449-73-4
• 化学式: C₁₀H₁₈O₂
• 分子量: 170.252
• InChiKey: UOOTWWIQOMIALC-UHFFFAOYSA-N

物化性质

• 沸点：
  219.3±39.0 °C(Predicted)
• 密度：
  0.92±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1,2-丙二烯,1-乙氧基- 、 异戊醛 以40%的产率得到3-Ethoxy-2-methylidene-4-(2-methylpropyl)oxetane
  参考文献：
  名称：

  Preparation of 2-alkylidene oxetanes: An investigation of the Paterno-Büchi reaction between aliphatic aldehydes and allenes

  摘要：

  Preliminary results of an examination of factors influencing the stoichiometry and regioselectivity of the Paterno-Buchi reaction between aliphatic aldehydes and nonsymmetrical allenes are divulged. Surprisingly little regioselectivity was seen with 3-methyl-1,2-butadiene (6); however, 1-ethoxy-1,2-propadiene (14) provided a single regioisomer. Copyright (C) 1996 Elsevier Science Ltd

  DOI：

  10.1016/s0040-4039(96)02001-1

文献信息

• Preparation of 2-alkylidene oxetanes: An investigation of the Paterno-Büchi reaction between aliphatic aldehydes and allenes
  作者：Amy R Howell、Rong Fan、Anh Truong

  DOI：10.1016/s0040-4039(96)02001-1

  日期：1996.11

  Preliminary results of an examination of factors influencing the stoichiometry and regioselectivity of the Paterno-Buchi reaction between aliphatic aldehydes and nonsymmetrical allenes are divulged. Surprisingly little regioselectivity was seen with 3-methyl-1,2-butadiene (6); however, 1-ethoxy-1,2-propadiene (14) provided a single regioisomer. Copyright (C) 1996 Elsevier Science Ltd