2-氨基-4-乙氧基-6-甲胺基-1,3,5-三嗪 | 62096-63-3

• 物质功能分类: 化学农药原药 - 除草剂 - 磺酰脲类除草剂
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三嗪类
• 中文名称: 2-氨基-4-乙氧基-6-甲胺基-1,3,5-三嗪
• 中文别名: 2-氨基-4-甲基氨基-6-乙氧基-1,3,5-三嗪；2-氨基-4-甲氨基-6-乙氧基-1,3,5-三嗪；2-氨基-4-甲胺基-6-乙氧基三嗪；胺苯三嗪
• 英文名称: 6-ethoxy-N-methyl-[1,3,5]triazine-2,4-diamine
• 英文别名: 6-ethoxy-N²-methyl-[1,3,5]triazine-2,4-diyldiamine；6-Aethoxy-N²-methyl-[1,3,5]triazin-2,4-diyldiamin；4-ethoxy-6-methylamino-1,3,5-triazin-2-amine；2-Amino-4-methylamino-6-ethoxy-1,3,5-triazin；2-Amino-6-ethoxy-4-methylamino-1,3,5-triazine；6-ethoxy-2-N-methyl-1,3,5-triazine-2,4-diamine
• CAS: 62096-63-3
• 化学式: C₆H₁₁N₅O
• 分子量: 169.186
• InChiKey: HEMSJLNVJJUYEU-UHFFFAOYSA-N

物化性质

• 熔点：
  171-174 °C (lit.)
• 沸点：
  365.9±25.0 °C(Predicted)
• 密度：
  1.288±0.06 g/cm3(Predicted)
• 稳定性/保质期：
  遵照规定使用和储存，则不会发生分解。

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  86
• 氢给体数：
  2
• 氢受体数：
  6

安全信息

• 危险品标志：
  Xn,Xi
• 危险类别码：
  R22,R36/37/38
• WGK Germany：
  1
• 安全说明：
  S26,S37/39
• 海关编码：
  2933699090
• 危险标志：
  GHS07
• 危险性描述：
  H302

SDS

Name:	2-Amino-4-methylamino-6-ethoxy-1 3 5-triazine Material Safety Data Sheet
Synonym:	None Known
CAS:	62096-63-3

Section 1 - Chemical Product MSDS Name:2-Amino-4-methylamino-6-ethoxy-1 3 5-triazine Material Safety Data Sheet
Synonym:None Known

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Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
62096-63-3	2-Amino-4-methylamino-6-ethoxy-1,3,5-t	ca. 100	unlisted

Hazard Symbols: XI
Risk Phrases: 36/37/38

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Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation. May cause chemical conjunctivitis.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled. Can produce delayed pulmonary edema.
Chronic:
No information found.

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Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:
Treat symptomatically and supportively.

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Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

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Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

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Section 7 - HANDLING and STORAGE
Handling:
Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing.
Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

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Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 62096-63-3: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

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Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Powder
Color: white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: Not available.
Specific Gravity/Density:
Molecular Formula: C6H11N5O
Molecular Weight: 169.19

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Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Dust generation, excess heat.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

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Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 62096-63-3 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
2-Amino-4-methylamino-6-ethoxy-1,3,5-triazine - Not listed by ACGIH, IARC, or NTP.

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Section 12 - ECOLOGICAL INFORMATION

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Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

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Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

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Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 62096-63-3: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 62096-63-3 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 62096-63-3 is not listed on the TSCA inventory.
It is for research and development use only.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

制备方法与用途

化学性质
本品为白色颗粒状晶体，熔点170～171℃，难溶于水，能溶解于热乙醇、丙酮等有机溶剂。

用途
2-氨基-4-甲氨基-6-乙氧基三嗪是合成磺酰脲类除草剂胺苯磺隆的中间体。

生产方法
其制备过程如下：首先在反应釜中加入溶剂，搅拌下逐步加入三聚氯氰。随后将温度降至-15℃并通入氨气，维持反应温度在-5～10℃之间，待达到预定量后升温至50℃，再通入一甲胺直至终点，保温反应后进行过滤，滤液回收溶剂，滤饼用水洗涤至中性，最后烘干得到2-氨基-4-甲氨基-6-氯三嗪。接着，在另一三嗪釜内加入溶剂和乙醇钠乙醇溶液，搅拌下加入上述制得的三嗪，升温回流并反应一定时间后趁热过滤，滤液结晶，再次过滤干燥即可获得成品。

反应信息

• 作为反应物：
  描述：

  2-异氰酸磺酰基苯甲酸甲酯 、 2-氨基-4-乙氧基-6-甲胺基-1,3,5-三嗪 以 二氯甲烷 为溶剂， 反应 1.0h， 以giving 0.9 g of the title compound, m.p. 204°-206° C.的产率得到胺苯磺隆
  参考文献：
  名称：

  Herbicidal sulfonylureas

  摘要：

  含有氨基取代杂环环的指定磺酰脲对油菜具有意外的选择性。

  公开号：

  US04548638A1

文献信息

• Herbicidal sulfonamides
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0196786A2

  公开（公告）日：1986-10-08

  Compounds of the formula: wherein R, is H or CH3; and R2 is H, F, Cl or CH3; exhibit herbicidal activity, especially selective activity on rape. The compounds may be made e.g. by reacting the appropriate arylsulfonyl isocyanate with the appropriate aminotriazine.

  式中 R 为 H 或 CH3，R2 为 H、F、Cl 或 CH3 的化合物具有除草活性，特别是对油菜具有选择性活性。 这些化合物可通过适当的芳基磺酰基异氰酸酯与适当的氨基三嗪反应制成。
• N-Azinyl-N'-(het)arylsulfonylharnstoffe als Herbizide
  申请人：BAYER AG

  公开号：EP0645386A1

  公开（公告）日：1995-03-29

  Die Erfindung betrifft neue N-Azinyl-N'-(het)arylsulfonylharnstoffe der Formel (I), in welcher Jfür J-1 bis J-4 steht, wobei J-1 bis J-4 folgende Bedeutungen haben: worin Efür eine direkte Bindung, Alkylen, Sauerstoff, Alkylamino oder Schwefel steht, und in welcher Afür N oder CR¹¹ steht (wobei die Reste R¹-R¹¹ die in der Beschreibung genannten Bedeutungen haben), mehrere Verfahren und neue Zwischenprodukte zu ihrer Herstellung sowie ihre Verwendung als Herbizide.

  本发明涉及式（I）的新型 N-氮基-N'-(het)芳基磺酰脲、 其中 J代表J-1至J-4，其中J-1至J-4的含义如下： 其中 E 代表直接键、亚烷基、氧、烷基氨基或硫、 其中 Are代表N或CR¹¹（R¹-R¹¹自由基的含义在描述中给出）、 制备和用作除草剂的几种工艺和新中间体。
• CURABLE COMPOSITION FOR TRANSFER MATERIAL AND PATTERN FORMATION METHOD
  申请人：SHOWA DENKO K.K.

  公开号：EP2345676A1

  公开（公告）日：2011-07-20

  An object of the invention is to provide curable compositions for transfer materials suited for nanoimprinting processes, which compositions have high dry etching resistance against argon gas and high selectivity of dry etching rate between by argon gas and by oxygen gas, and can be fabricated into fine patterns used as resists or the like. A curable composition for transfer materials includes a (meth)acrylate compound having a triazine skeleton which is obtainable by reacting an aminotriazine compound, a compound having a hydroxyl group and a (meth) acryloyl group in the molecule, and an aldehyde.

  本发明的目的是提供适用于纳米压印工艺的转印材料的可固化组合物，该组合物对氩气具有高抗干蚀刻性，对氩气和氧气的干蚀刻率具有高选择性，并可制成用作抗蚀剂等的精细图案。用于转印材料的可固化组合物包括一种具有三嗪骨架的（甲基）丙烯酸酯化合物，该化合物可通过氨基三嗪化合物、分子中具有羟基和（甲基）丙烯酰基的化合物以及醛的反应而获得。
• HAGEMAN, L. H.;ROY, G. A. ,, JR.
  作者：HAGEMAN, L. H.、ROY, G. A. ,, JR.

  DOI：——

  日期：——
• CURABLE COMPOSITION FOR TRANSFER MATERIALS, AND PATTERN FORMING PROCESS
  申请人：Arai Yoshikazu

  公开号：US20110206834A1

  公开（公告）日：2011-08-25

  An object of the invention is to provide curable compositions for transfer materials suited for nanoimprinting processes, which compositions have high dry etching resistance against argon gas and high selectivity of dry etching rate between by argon gas and by oxygen gas, and can be fabricated into fine patterns used as resists or the like. A curable composition for transfer materials includes a (meth)acrylate compound having a triazine skeleton which is obtainable by reacting an aminotriazine compound, a compound having a hydroxyl group and a (meth)acryloyl group in the molecule, and an aldehyde.