N-(3-imidazolyl)propyl dansylamide | 1350462-51-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: N-(3-imidazolyl)propyl dansylamide
• 英文别名: 5-(dimethylamino)-N-(3-imidazol-1-ylpropyl)naphthalene-1-sulfonamide
• CAS: 1350462-51-9
• 化学式: C₁₈H₂₂N₄O₂S
• 分子量: 358.464
• InChiKey: NWVASVKWMQJBRC-UHFFFAOYSA-N

物化性质

• 沸点：
  587.3±60.0 °C(Predicted)
• 密度：
  1.25±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  25
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  75.6
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  N-(3-imidazolyl)propyl dansylamide 以 水 、 甲苯 为溶剂， 反应 60.0h， 生成 1-(3-((5-(dimethylamino)naphthalene)-1-sulfonamido)propyl)-3-ethyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide
  参考文献：
  名称：

  Ionic liquidized-naphthalenesulfonamide: successful fabrication of liquid fluorescent materials

  摘要：

  一种新的液体荧光有机盐类通过离子液体化策略被设计和制备。这些新的离子液体材料在紫外照射下表现出强烈的绿色荧光和显著的溶剂依赖性光致发光。对它们的物理化学性质，特别是荧光行为进行了深入研究。

  DOI：

  10.1039/c1jm13828f
• 作为产物：
  描述：

  1-(3-氨基丙基)咪唑 、 丹酰氯 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 1.0h， 以77%的产率得到N-(3-imidazolyl)propyl dansylamide
  参考文献：
  名称：

  Fluorogenic dansyl-ligated gold nanoparticles for the detection of sulfur mustard by displacement assay

  摘要：

  通过咪唑和氨基组将丹萘荧光染料连接到金纳米颗粒上，所得到的结合物能够通过荧光开关“开启”位移测定法检测微摩尔浓度的化学战剂芥子气。

  DOI：

  10.1039/c3cc39105a

文献信息

• Fluorogenic dansyl-ligated gold nanoparticles for the detection of sulfur mustard by displacement assay
  作者：Richard C. Knighton、Mark R. Sambrook、Jack C. Vincent、Simon A. Smith、Christopher J. Serpell、James Cookson、Matthew S. Vickers、Paul D. Beer

  DOI：10.1039/c3cc39105a

  日期：——

  The dansyl fluorophore ligated to gold nanoparticles via imidazole and amine groups affords conjugates capable of detecting micromolar concentrations of the chemical warfare agent sulfur mustard by a fluorescence switching ‘ON’ displacement assay.

  通过咪唑和氨基组将丹萘荧光染料连接到金纳米颗粒上，所得到的结合物能够通过荧光开关“开启”位移测定法检测微摩尔浓度的化学战剂芥子气。
• 수은 이온 검출용 화학 센서
  申请人：Kyungpook National University Industry-Academic Cooperation Foundation 경북대학교 산학협력단(220040016844) BRN ▼504-82-09678

  公开号：KR101521757B1

  公开（公告）日：2015-05-19

  수은 이온 검출용 화학 센서는 하기 화학식 1로 나타내는 화합물을 포함한다.[화학식 1] 화학식 1에서, n은 2 내지 5의 정수를 나타낸다.

  汞离子检测化学传感器包括化合物，其表示为化学式1。在化学式1中，n代表一个介于2到5之间的整数。
• A self-assembled amphiphilic imidazolium-based ATP probe
  作者：Jiang-Hua Zhu、Chuan Yu、Yong Chen、Jinwoo Shin、Qian-Yong Cao、Jong Seung Kim

  DOI：10.1039/c7cc01346a

  日期：——

  An amphiphilic imidazolium-based self-assembled probe forms aggregates and selectively recognizes aqueous ATP among other bioactive anions with a significant enhancement in fluorescence emission.

  一种基于咪唑鎓的两亲性自组装探针会形成聚集体，并在其他生物活性阴离子中选择性地识别水体中的 ATP，同时显著增强荧光发射。
• Ionic liquidized-naphthalenesulfonamide: successful fabrication of liquid fluorescent materials
  作者：Qinghua Zhang、Benqun Yang、Shiguo Zhang、Shimin Liu、Youquan Deng

  DOI：10.1039/c1jm13828f

  日期：——

  A new class of liquid fluorescent organic salts was designed and prepared through via a strategy of ionic liquidization. These new ionic liquid materials exhibited strong green fluorescence and remarkable solvent-dependent photoluminescence under UV irradiation. Their physicochemical properties, especially the fluorescent behaviour, were studied intensively.

  一种新的液体荧光有机盐类通过离子液体化策略被设计和制备。这些新的离子液体材料在紫外照射下表现出强烈的绿色荧光和显著的溶剂依赖性光致发光。对它们的物理化学性质，特别是荧光行为进行了深入研究。
• N-(3-Imidazolyl)propyl dansylamide as a selective Hg2+ sensor in aqueous media through electron transfer
  作者：Ashwani Kumar、Hong-Seok Kim

  DOI：10.1016/j.saa.2015.03.091

  日期：2015.9

  N-Imidazolylpropyl dansylamide I was synthesized for the sensing of metal ions and found to be selective and sensitive toward Hg2+ ions in a PBS-EtOH (1:4, pH = 7.4) solution. The sensing ability of probe 1 was examined by UV-Vis, fluorescence, and H-1 NMR spectroscopy. The sensing of Hg2+ exhibited a quenching of emission band at lambda(max) = 515 nm of probe I, which was associated with quenching of green fluorescence emission under 365 nm illumination. Probe 1 showed a good association constant with Hg2+ (K-a = 6.48 x 10(4) M-1) with a stoichiometry of 1:1 in PBS-EtOH (1:4, pH = 7.4) having the lowest detection limit of 1 mu M for Hg2+; on the other hand, probe 2, which has no imidazole moiety, was not able to detect any metal ion. In the case of probe 1, electrons on the imidazole nitrogen are available for electron transfer (ET), which was responsible for its green emission band that was quenched on addition of Hg2+; this clearly indicates that these electrons were used for the formation of a coordinate bond with Hg2+ and that ET was switched off. (C) 2015 Elsevier B.V. All rights reserved.