hexahydrocannabinol | 1972-09-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: hexahydrocannabinol
• 英文别名: (6aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-ol
• CAS: 1972-09-4；6692-85-9；23050-51-3；23050-52-4；36403-90-4；36403-91-5；58617-32-6；58617-33-7；59042-47-6；69855-11-4；69855-12-5；69855-14-7；69880-65-5；103476-58-0；146338-70-7
• 化学式: C₂₁H₃₂O₂
• 分子量: 316.484
• InChiKey: XKRHRBJLCLXSGE-BDVYOWHSSA-N

物化性质

• 沸点：
  390.2±31.0 °C(Predicted)
• 密度：
  0.993±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7.8
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Compositions and methods for reducing overdose
  申请人：Odidi Isa

  公开号：US10293046B2

  公开（公告）日：2019-05-21

  Drug delivery formulations, uses thereof and methods of making same are provided in order to reduce the potential for abuse, misuse or improper administration of an addictive substance or any active substance and to prevent, reduce, inhibit, or delay purposeful or accidental overdose of an active substance by ingesting too many dosage forms at once, for example.

  提供给药制剂、其用途和制作方法是为了减少滥用、误用或不当使用成瘾物质或任何活性物质的可能性，并防止、减少、抑制或延缓因一次摄入过多剂型的活性物质而有目的或意外地过量使用。
• Process for producing an extract containing tetrahydrocannabinol and cannabidiol from cannabis plant material, and cannabis extracts
  申请人：Bionorica Ethics GmbH

  公开号：US10870632B2

  公开（公告）日：2020-12-22

  The invention relates to a method for producing an extract from cannabis plant matter, containing tetrahydrocannabinol, cannabidiol and optionally the carboxylic acids thereof. According to said method, the dried pint matter is ground and subjected to a CO2 extraction and the primary extract obtained is separated. The invention method permits Δ8 or Δ9 tetrahydrocannabinol to be selectively obtained both from industrial hemp and from drug-producing hemp, optionally after dissolving the primary extract in ethanol, separating undesirable waxes and removing the solvent under reduced pressure.

  本发明涉及一种从含有四氢大麻酚、大麻二酚和可选羧酸的大麻植物物质中提取物的生产方法。根据上述方法，将干燥的品脱物磨碎并进行二氧化碳萃取，然后分离得到初级提取物。本发明方法允许从工业大麻和药物生产大麻中选择性地获得 Δ8 或 Δ9 四氢大麻酚，可选择将初级提取物溶解在乙醇中，分离不需要的蜡，并在减压下去除溶剂。
• Application System for a Plaster Containing an Active Ingredient and a Controlled-Release Agent for Said Active Ingredient
  申请人：Bartholomaus Johannes

  公开号：US20080274146A1

  公开（公告）日：2008-11-06

  The present invention relates to an application system for an active ingredient release system, comprising a film-form application strip, which is in each case bonded detachably to an active ingredient-containing plaster and a separate active ingredient release regulator separate there from.
• Abuse-Resistant Pharmaceutical Dosage Form
  申请人：Bartholomäus Johannes

  公开号：US20100221322A1

  公开（公告）日：2010-09-02

  A solid pharmaceutical dosage form that is safeguarded against abuse containing at least one active substance that could be subject to abuse and at least one antagonist for the active substance, which antagonist is spatially separate from the active substance. The active substance or substances is/are present in at least one subunit (a), and the at least one antagonist is present in at least one subunit (b), and the at least one antagonist in subunit (b) is to all intents and purposes not released in the body if the dosage form is correctly administered as prescribed.
• PROCESS FOR PRODUCING AN EXTRACT CONTAINING TETRAHYDROCANNABINOL AND CANNABIDIOL FROM CANNABIS PLANT MATERIAL, AND CANNABIS EXTRACTS
  申请人：Delta-9-Pharma GmbH

  公开号：US20140248379A1

  公开（公告）日：2014-09-04

  The invention relates to a method for producing an extract from cannabis plant matter, containing tetrahydrocannabinol, cannabidiol and optionally the carboxylic acids thereof. According to said method, the dried pint matter is ground and subjected to a CO 2 extraction and the primary extract obtained is separated. The invention method permits Δ 8 or Δ 9 tetrahydrocannabinol to be selectively obtained both from industrial hemp and from drug-producing hemp, optionally after dissolving the primary extract in ethanol, separating undesirable waxes and removing the solvent under reduced pressure.