2,4,6,8-tetraisopropoxy-2,4,6,8-tetramethylcyclotetrasiloxane | 18547-01-8

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: 2,4,6,8-tetraisopropoxy-2,4,6,8-tetramethylcyclotetrasiloxane
• 英文别名: 2,4,6,8-tetramethyl-2,4,6,8-tetraisopropoxycyclotetrasiloxane；2,4,6,8-Tetramethyl-2,4,6,8-tetraisopropoxy-cyclotetrasiloxan；2,4,6,8-Tetramethyl-2,4,6,8-tetra(propan-2-yloxy)-1,3,5,7,2,4,6,8-tetraoxatetrasilocane
• CAS: 18547-01-8
• 化学式: C₁₆H₄₀O₈Si₄
• 分子量: 472.831
• InChiKey: VSLWOJSXHMCNON-UHFFFAOYSA-N

物化性质

• 沸点：
  335.6±25.0 °C(Predicted)
• 密度：
  1.01±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.04
• 重原子数：
  28
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  73.8
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  dichloro-isopropoxy-methyl-silane 在 吡啶 作用下， 生成 2,4,6,8-tetraisopropoxy-2,4,6,8-tetramethylcyclotetrasiloxane
  参考文献：
  名称：

  Alkylalkoxypolysiloxanes. VIII. Lower Members of Cyclic Methyl- and Ethyl-isopropoxypolysiloxanes

  摘要：

  1) 使用吡啶作为酸受体，以相当大的滴速水解甲基-和乙基-异丙氧基二氯硅烷。2) 制备并表征了甲基-和乙基-异丙氧基环三硅氧烷。发现这些化合物是稳定的。3)已制备并表征了甲基-和乙基-异丙氧基环四硅氧烷。

  DOI：

  10.1246/bcsj.33.659

文献信息

• Syntheses and Properties of Sila-Functional Oligosiloxanes—Linear and Cyclic Tetrasiloxanes with Methyl and Vinyl Groups—
  作者：Takahiro Gunji、Miho Watanabe、Koji Abe、Yoshimoto Abe

  DOI：10.1246/bcsj.76.341

  日期：2003.2

  The syntheses of the titled oligosiloxanes by controlled hydrolysis of the corresponding isocyanatosilanes under vapor phase or in THF (or THF/ether) were investigated. The vapor phase hydrolysis of RSi(NCO)3 (R = Me, Vinyl) with a water–1,4-dioxane vapor gave the disiloxanes [R(OCN)2Si]2O in yields of 85% (R = Me) and 90% (R = Vinyl). Further vapor phase hydrolysis of the disiloxanes provided the linear tetrasiloxanes NCO[SiR(NCO)O]3SiR(NCO)2 in yields of 71% (R = Me) and 69% (R = Vinyl). The cyclotetrasiloxanes [R(OCN)SiO]4 were synthesized in yields of 12% (R = Me) and 33% (R = Vinyl) or 24% (R = Me) and 58% (R = Vinyl) by hydrolysis of the disiloxanes or of the linear tetrasiloxanes in THF, respectively. On the other hand, the linear tetrasiloxanes OCN[SiR(OPri)O]3SiR(OPri)(NCO) were obtained in yields of 50% (R = Me) and 56% (R = Vinyl) by hydrolysis of [R(OCN)(PriO)Si]2O prepared from RSi(OPri)(NCO)2 under mild conditions in THF/ether, while the cyclic tetrasiloxanes [R(PriO)SiO]4 were afforded in the yield of 61–62% by hydrolysis of the disiloxanes under more severe conditions in THF.

  研究人员通过在气相或 THF（或 THF/乙醚）中控制相应异氰酸硅烷的水解，合成了标题低硅氧烷。RSi(NCO)3（R = Me，Vinyl）与水-1,4-二氧六环蒸汽的气相水解得到了二硅氧烷[R(OCN)2Si]2O，产率分别为 85%（R = Me）和 90%（R = Vinyl）。进一步对二硅氧烷进行气相水解，可得到线性四硅氧烷 NCO[SiR(NCO)O]3SiR(NCO)2 ，产率分别为 71%（R = Me）和 69%（R = Vinyl）。通过在 THF 中水解二硅氧烷或线型四硅氧烷，合成了环四硅氧烷 [R(OCN)SiO]4，产率分别为 12%（R = Me）和 33%（R = 乙烯基），或 24%（R = Me）和 58%（R = 乙烯基）。另一方面，由 RSi(OPri)(NCO)2制备的[R(OCN)(PriO)Si]2O在 THF/乙醚中的温和条件下水解得到线性四硅氧烷 OCN[SiR(OPri)O]3SiR(OPri)(NCO)，产率分别为 50%（R = Me）和 56%（R = Vinyl）、而环状四硅氧烷[R(PriO)SiO]4 则是在 THF 中以更苛刻的条件水解二硅氧烷得到的，产率为 61-62%。
• EP1845100
  申请人：——

  公开号：——

  公开（公告）日：——
• Alkylalkoxypolysiloxanes. VIII. Lower Members of Cyclic Methyl- and Ethyl-isopropoxypolysiloxanes
  作者：Rokuro Okawara、Masuo Katayama

  DOI：10.1246/bcsj.33.659

  日期：1960.5

  1) Methyl- and ethyl-isopropoxydichlorosilane were hydrolyzed with considerable dropping rate using pyridine as an acid acceptor.2) Methyl- and ethyl-isopropoxycyclotrisiloxane have been prepared and characterized. Those compounds were found to be stable.3) Methyl- and ethyl-isopropoxycyclotetrasiloxane have been prepared and characterized.

  1) 使用吡啶作为酸受体，以相当大的滴速水解甲基-和乙基-异丙氧基二氯硅烷。2) 制备并表征了甲基-和乙基-异丙氧基环三硅氧烷。发现这些化合物是稳定的。3)已制备并表征了甲基-和乙基-异丙氧基环四硅氧烷。