Spiro(isobenzofuran-1(3H),9'-(9H)xanthene)-6-carboxamide, 3',6'-bis(acetyloxy)-N-(3-(3-(2,5-dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl)-1H-indol-1-yl)propyl)-3-oxo- | 150206-02-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: Spiro(isobenzofuran-1(3H),9'-(9H)xanthene)-6-carboxamide, 3',6'-bis(acetyloxy)-N-(3-(3-(2,5-dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl)-1H-indol-1-yl)propyl)-3-oxo-
• 英文别名: [6'-acetyloxy-6-[3-[3-[4-(1-methylindol-3-yl)-2,5-dioxopyrrol-3-yl]indol-1-yl]propylcarbamoyl]-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl] acetate
• CAS: 150206-02-3
• 化学式: C₄₉H₃₆N₄O₁₀
• 分子量: 840.846
• InChiKey: JWPRTLPEVKPSEG-UHFFFAOYSA-N

物化性质

• 密度：
  1.45±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  63
• 可旋转键数：
  11
• 环数：
  10.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  173
• 氢给体数：
  2
• 氢受体数：
  10

反应信息

• 作为产物：
  描述：

  3-[1-(3-氨基丙基)吲哚-3-基]-4-(1-甲基吲哚-3-基)吡咯-2,5-二酮 、 (2,5-Dioxopyrrol-1-yl) 3',6'-diacetyloxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxylate 在 PS-thiophenol resin 、 三丁基膦 、 i-Pr₂NEt₂ 作用下， 生成 Spiro(isobenzofuran-1(3H),9'-(9H)xanthene)-6-carboxamide, 3',6'-bis(acetyloxy)-N-(3-(3-(2,5-dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl)-1H-indol-1-yl)propyl)-3-oxo-
  参考文献：
  名称：

  Polymer-bound N-hydroxysuccinimide esters: A column-free fluorescent-labeling method

  摘要：

  Polymer-bound N-hydroxysuccinimide esters of 1-pyrenebutyric acid, 6-carboxyfluorescein diacetate, and biotin were efficiently prepared. Column-free fluorescent- and biotin-labeling reactions of various amines using these resins were successfully demonstrated. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(99)00091-8