N-lithio 1-aminonaphthalene | 30897-53-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: N-lithio 1-aminonaphthalene
• 英文别名: N-lithio-1-naphthylamine；lithium 1-naphthylamide；[1]naphthylamine; lithium-salt；[1]Naphthylamin; Lithium-Salz；1-Lithiumaminonaphthalin；Lithium;naphthalen-1-ylazanide
• CAS: 30897-53-1；137059-03-1
• 化学式: C₁₀H₈LiN
• 分子量: 149.121
• InChiKey: BLZRQSWKULCZJG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.53
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N-lithio 1-aminonaphthalene 、 8-[Chloro-(toluene-4-sulfinyl)-methylene]-1,4-dioxa-spiro[4.5]decane 在 叔丁基氯化镁 、 异丙基氯化镁 作用下， 以 甲苯 为溶剂， 反应 0.17h， 以66%的产率得到2-(1,4-dioxaspiro[4.5]dec-8-ylidenemethyl)naphthalen-1-ylamine
  参考文献：
  名称：

  芳胺在邻位的直接烯基化

  摘要：

  镁烷叉卡宾的治疗，这是从1氯乙烯基生成p -甲苯基砜与异丙基氯化镁在甲苯中-78℃下，用Ñ -lithio芳基胺，得到邻-alkenylated芳基胺在中度至良好的产率。发现该反应在类胡萝卜素碳上以高度立体定向的方式进行。该反应在芳环的邻位提供芳胺的相当新颖和直接的烯基化。

  DOI：

  10.1016/j.tetlet.2004.06.024

文献信息

• ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME
  申请人：Samsung Display Co., Ltd.

  公开号：US20170077427A1

  公开（公告）日：2017-03-16

  An organic light-emitting device includes: a first electrode; a second electrode facing the first electrode; and an organic layer between the first electrode and the second electrode, the organic layer including an emission layer, wherein the organic layer includes a condensed cyclic compound represented by Formula 1. An organic light-emitting device including the organometallic compound according to the embodiments of the present disclosure may have high efficiency: M(L 1 )(L 2 ).   Formula 1

  一种有机发光器件包括：第一电极；朝向第一电极的第二电极；以及位于第一电极和第二电极之间的有机层，该有机层包括一个发射层，其中有机层包括由式1表示的缩合环化合物。根据本公开的实施例，包括有机金属化合物的有机发光器件可能具有高效率：M(L1)(L2)。
• Fragmentation of an imido tin(II) cubane; syntheses and structures of heterobimetallic complexes containing tin(II) imido and phosphinidine anions
  作者：Robert E. Allan、Michael A. Beswick、Natalie L. Cromhout、Michael A. Paver、Paul R. Raithby、Alexander Steiner、Mark Trevithick、Dominic S. Wright

  DOI：10.1039/cc9960001501

  日期：——

  The reactions of the imido tin(II) cubane [SnNBut]4 with 3 equiv. of [C10H7NHLi](C10H7= 1-naphthyl) and 6 equiv. of [C6H11PHLi](C6H11= cyclohexyl) produce [LI(thf)4]+[(ButN)(C10H7N)3Sn3Li·thf]–·thf·PhMe 1 and [Sn2(PC6H11)3}2Li4·4thf]·2thf 2, respectively, containing the first structurally characterized polyimido and polyphosphinidine anions of a divalent group 14 metal.

  亚胺锡(II)立方烷[SnNBut]4与3当量的[C10H7NHLi](C10H7=1-萘基)和6当量的[C6H11PHLi](C6H11=环己基)的反应分别生成[LI(thf)4]+[(ButN)(C10H7N)3Sn3Li·thf]–·thf·PhMe 1和[Sn2(PC6H11)3}2Li4·4thf]·2thf 2，其中包含第一个结构特征为二价14族金属的聚亚胺和聚磷腈阴离子。
• Cyclopropylation of arylamines at the 2-position with cyclopropylmagnesium carbenoids
  作者：Yukie Yamada、Mirai Mizuno、Shinobu Nagamoto、Tsuyoshi Satoh

  DOI：10.1016/j.tet.2009.09.096

  日期：2009.11

  Direct cyclopropylation of arylamines at the 2-position with 1-chlorocyclopropyl phenyl sulfoxides was achieved. The reaction of N-lithio arylamines with cyclopropylinagnesium carbenoids, which are generated from 1-chlorocyclopropyl phenyl sulfoxides with i-PrMgCl via the sulfoxide-magnesium exchange reaction, is the key of this procedure, This method offers an unprecedented way for the synthesis of arylamines having a cyclopropane ring at the 2-position directly from arylamines. (C) 2009 Elsevier Ltd. All rights reserved.
• Direct alkenylation of arylamines at the ortho-position
  作者：Tsuyoshi Satoh、Yumi Ogino、Masatomo Nakamura

  DOI：10.1016/j.tetlet.2004.06.024

  日期：2004.7

  gave ortho-alkenylated arylamines in moderate to good yields. The reaction was found to proceed in a highly stereospecific manner at the carbenoid carbon. This reaction offers a quite novel and direct alkenylation of arylamines at the ortho-position of the aromatic ring.

  镁烷叉卡宾的治疗，这是从1氯乙烯基生成p -甲苯基砜与异丙基氯化镁在甲苯中-78℃下，用Ñ -lithio芳基胺，得到邻-alkenylated芳基胺在中度至良好的产率。发现该反应在类胡萝卜素碳上以高度立体定向的方式进行。该反应在芳环的邻位提供芳胺的相当新颖和直接的烯基化。