4-methylphenol-d | 2876-04-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 4-methylphenol-d
• 英文别名: O-deuterio-4-methyl-phenol；1-Deuteriooxy-4-methylbenzene
• CAS: 2876-04-2
• 化学式: C₇H₈O
• 分子量: 109.132
• InChiKey: IWDCLRJOBJJRNH-DYCDLGHISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  [bis(dimethylphosphanylmethyl)-methylsilyl]methyl-dimethylphosphane;ruthenium(1+) monohydride;trimethylphosphane 、 4-methylphenol-d 以 苯 为溶剂， 生成
  参考文献：
  名称：

  Regiocontrol of Cyclometalation in a P₄Ru(II) System. Unusual Base-Induced Metalation within a Chelate Ring versus Activation of a Methyl Group

  摘要：

  The internally cyclometalated complex (MeSi-(CH2PMe2)(2)CHPMe2)(PMe3)RuH has been prepared by the treatment of MeSi(CH2PMe2)(3)PMe3Ru(H)(Cl) with base, and an analogue has been structurally characterized by X-ray diffraction. The externally cyclometalated isomer MeSi(CH2PMe2)(3)PMe2CH2RuH has been cleanly generated by the thermolysis of MeSi(CH2PMe2)(3)PMe3-Ru(H)(Me), and the two isomers have been contrasted in terms of their spectroscopic features, calculated energies, and relative reactivities toward cresol and H-2. The two isomers are surprisingly resistant to interconversion. A chloride derivative, (MeSi(CH2PMe2)(2)CHPMe2)(PMe3)-RuCl, has also been prepared, and its reactivity has shown the internally cyclometalated framework to be surprisingly stable.

  DOI：

  10.1021/om0202470
• 作为产物：
  描述：

  对甲酚 在 硫酸 、 sodium 、 氘代盐酸 作用下， 以 乙醚 为溶剂， 反应 25.0h， 生成 4-methylphenol-d
  参考文献：
  名称：

  2-亚硝酸甲氧基乙酯作为化学选择性水硝化试剂

  摘要：

  已经开发了一种允许对酪氨酸和酚进行化学选择性硝化的水上方法。水在反应过程中的诱人作用为合成有机化学系统的设计提供了新的探索途径。

  DOI：

  10.1002/asia.202200457

文献信息

• Zinc-Mediated Efficient and Selective Reduction of Carbonyl Compounds
  作者：Tirtha Mandal、Snehasish Jana、Jyotirmayee Dash

  DOI：10.1002/ejoc.201700887

  日期：2017.9.8

  Simple yet unknown! Aldehydes and ketones can be easily reduced to the corresponding alcohols with Zn/NH4Cl, which is used for pinacol coupling reactions. Chemoselective reduction of aldehydes in the presence of ketones is achieved. Isatins can be efficiently reduced at the C3 position.

  简单而未知！醛和酮可通过Zn / NH 4 Cl轻松还原为相应的醇，用于频哪醇偶联反应。在酮存在下实现了醛的化学选择性还原。可以在C3位置上有效地减少Isatins。
• AKHTAR M. N.; BOYD D. R.; NEILL J. D.; JERINA D. M., J. CHEM. SOC., PERKIN TRANS., 1980, PART 1, NO 8, 1693-1699
  作者：AKHTAR M. N.、 BOYD D. R.、 NEILL J. D.、 JERINA D. M.

  DOI：——

  日期：——
• PATRICK, T. B.;WILLAREDT, R. P.;DEGONIA, D. J., J. ORG. CHEM., 1985, 50, N 13, 2232-2235
  作者：PATRICK, T. B.、WILLAREDT, R. P.、DEGONIA, D. J.

  DOI：——

  日期：——
• NOVOLAC-BASED EPOXY COMPOUND, PRODUCTION METHOD FOR SAME, COMPOSITION AND CURED ARTICLE COMPRISING SAME, AND USE FOR SAME
  申请人：KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY

  公开号：US20150203626A1

  公开（公告）日：2015-07-23

  A novolac epoxy compound having an alkoxysilyl group of which composite has low CTE and increase of glass transition temperature, and requiring no coupling agent, a production method thereof, an epoxy composition including the same and a cured article thereof, are provided. A novolac epoxy compound having an alkoxysilyl group of Formulae I-1 to I-4, a production method of the novolac epoxy compound having an alkoxysilyl group by the epoxidation, alkenylation and alkoxysilylation of a novolac epoxy compound, a production method of the novolac epoxy compound having an alkoxysilyl group by the epoxidation and alkoxysilylation of a novolac epoxy compound, an epoxy composition including the novolac epoxy compound having an alkoxysilyl group, and a cured article, are provided. The cured article, i.e., the composite of the epoxy composition has improved chemical bonding efficiency due to alkoxysilyl groups. Low CTE and high glass transition temperature are exhibited
• NOVEL NOVOLAC CURING AGENT WITH ALKOXYSILYL GROUP, METHOD FOR PREPARING THE SAME, COMPOSITION CONTAINING THE SAME, THE CURED PRODUCT, AND USE THEREOF
  申请人：KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY

  公开号：US20160326299A1

  公开（公告）日：2016-11-10

  A new novolac curing agent with an alkoxysilyl group exhibiting excellent heat resistance such as a low CTE and an high Tg when a composite is formed, a preparing method of the same, a composition including the same, a cured article, and an use thereof, are provided. The new novolac curing agent having an alkoxysilyl group of Formulae I-1 to I-4, a preparing method of the new novolac curing agent by alkenylation and alkoxysilylation of the novolac curing agent, a preparing method of the new novolac curing agent by alkoxysilylation of a novolac curing agent, a composition including a novolac curing agent having an alkoxysilyl group of Formulae I-1 to I-4, a cured article and a use thereof, are provided. A composite including a novel novolac curing agent having an alkoxysilyl group exhibits a low CTE and a high glass transition temperature.