9H-xanthen-1-ol | 106594-25-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 9H-xanthen-1-ol
• 英文别名: xanthen-1-ol；Hydroxyxanthene
• CAS: 106594-25-6
• 化学式: C₁₃H₁₀O₂
• 分子量: 198.221
• InChiKey: BJIZDEKNRFATGL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  9H-xanthen-1-ol 在 chromium(VI) oxide 、 4-甲基苯磺酸吡啶 作用下， 以 吡啶 、 氯仿 为溶剂， 反应 76.0h， 生成 2,2-diphenyl-2H-pyrano[2,3-a]xanthen-12(12H)-one
  参考文献：
  名称：

  Synthesis and Photochromic Behavior of Novel Annelated 2H-Chromenes Derived from Hydroxy-9H-xanthen-9-ones

  摘要：

  The synthesis of four novel pyrano-xanthenones derived from hydroxy-9H-xanthen-9-ones is described, and their photochromic properties in solution are reported. All compounds synthesized exhibit a good colorability, making them good potential dyes. The presence of the chromone system fused in the 7,8-position seems to lead to more stabilized colored forms.

  DOI：

  10.1002/1522-2675(20010131)84:1<117::aid-hlca117>3.0.co;2-f
• 作为产物：
  描述：

  1-benzenesulfonyloxy-xanthen-9-one 在 lithium aluminium tetrahydride 、 乙醚 、 苯 作用下， 生成 9H-xanthen-1-ol
  参考文献：
  名称：

  Reactions of Hydroxyxanthones. IV.¹ Action of Lithium Aluminum Hydride and of Diazomethane on Hydroxyxanthones

  摘要：

  DOI：

  10.1021/jo01363a029

文献信息

• SecA Inhibitors and Methods of Making and Using Thereof
  申请人：Georgia State University Research Foundation, Inc.

  公开号：US20150152077A1

  公开（公告）日：2015-06-04

  Inhibitors of SecA, and methods of making and using thereof, are described herein. The compounds described herein can be used to treat or prevent microbial infections, such as bacterial infections.

  本文介绍了SecA的抑制剂及其制备和使用方法。本文所描述的化合物可用于治疗或预防微生物感染，如细菌感染。
• Compositions and methods for combating the appearance of ageing
  申请人：L'OREAL

  公开号：US20020197289A1

  公开（公告）日：2002-12-26

  The present invention relates to a composition, especially a cosmetic composition, containing fibers and at least one anti-ageing active agent. The composition may be used to camouflage skin imperfections and to treat signs of ageing of the skin. The invention also relates to a composition containing fibers and at least one vitamin chosen from vitamin C, vitamin B3, vitamin B5, vitamin D, vitamin F, derivatives thereof, analogues thereof, precursors thereof and mixtures thereof, or from enzymes, steroids, and flavonoids.

  本发明涉及一种组合物，特别是一种化妆品组合物，包含纤维和至少一种抗衰老活性剂。该组合物可用于掩盖皮肤缺陷并治疗皮肤衰老迹象。本发明还涉及一种含有纤维和至少一种维生素的组合物，所述维生素选自维生素C、维生素B3、维生素B5、维生素D、维生素F、其衍生物、类似物、前体和混合物，或选自酶、类固醇和类黄酮。
• Process for preparing alpha,alpha-disubstituted aromatics and heteroaromatics as cognition enhancers
  申请人：THE DU PONT MERCK PHARMACEUTICAL COMPANY

  公开号：EP0532054A1

  公开（公告）日：1993-03-17

  Cognitive defeciencies or neurological dysfunction in mammals are treated with α,α-disubstituted aromatic or heteroaromatic compounds. The compounds have the formula: or a salt thereof    wherein X and Y are taken together to form a saturated or unsaturated carbocyclic or heterocyclic first ring and the shown carbon in said ring is α to at least one additional aromatic ring or heteroaromatic ring fused to the first ring;    one of Het¹ or Het² is 2, 3, or 4-pyridyl or 2, 4, or 5-pyrimidinyl and the other is selected from (a) 2, 3, or 4-pyridyl, (b) 2, 4, or 5-pyrimidinyl, (c) 2-pyrazinyl, (d) 3, or 4-pyridazinyl, (e) 3, or 4-pyrazolyl, (f) 2, or 3-tetrahydrofuranyl, and (g) 3-thienyl.

  α，α-二取代芳香族或杂芳族化合物可治疗哺乳动物的认知缺陷或神经功能障碍。这些化合物的化学式如下 或其盐 其中 X 和 Y 共同形成饱和或不饱和碳环或杂环的第一环，所述环中所示碳与融 入第一环的至少一个附加芳环或杂芳环相连； Het¹ 或 Het² 中的一个是 2、3 或 4-吡啶基或 2、4 或 5-嘧啶基，另一个选自以下各项 (a) 2、3 或 4-吡啶基、 (b) 2、4 或 5-嘧啶基、 (c) 2-吡嗪基、 (d) 3 或 4-哒嗪基、 (e) 3 或 4-吡唑基、 (f) 2 或 3-四氢呋喃基，以及 (g) 3-噻吩基。
• METHOD OF PROVIDING PREPARATION FOR TOPICAL APPLICATION AND SUPPLEMENT MEETING CLIENT'S NEEDS
  申请人：Ajinomoto Co., Inc.

  公开号：EP1914678A1

  公开（公告）日：2008-04-23

  The present invention provides a method of efficiently providing, to a client, a preparation for topical application and a supplement suitable for the client, which includes inputting a part desired by the client to be improved and an improvement effect desired for the part, determining, based on the information and by a computer, a composition of nutritional components suitable for the improvement effect desired for the part to be improved, determining a preparation for topical application for delivering the selected nutritional components to the part to be improved, determining a supplement containing the selected composition of nutritional components by referring to the database, in which compositions of nutritional components of supplements are registered in advance, and outputting the information of the selected supplement and preparation for topical application.

  本发明提供了一种向客户有效提供局部应用制剂和适合客户的补充剂的方法，该方法包括输入客户希望改善的部位和该部位希望达到的改善效果，根据信息并通过计算机确定适合待改善部位希望达到的改善效果的营养成分组成、确定用于将所选营养成分输送到待改善部位的局部应用制剂，通过参考数据库确定含有所选营养成分组合的补充剂，其中补充剂的营养成分组合已预先注册，并输出所选补充剂和局部应用制剂的信息。
• WATER-BASED CELL STAINING COMPOSITION, METHOD FOR PREPARING SAME AND USE THEREOF, CELL SAMPLE PREPARATION AND CELL COUNTING METHODS
  申请人：Quintino De Oliveira, Henrique Jesus

  公开号：EP3392343A1

  公开（公告）日：2018-10-24

  The present invention relates to a cell dye composition characterized in that it comprises methyl green or an equivalent of its chemical group triarylmethanes (or triphenylmethanes), pironin or an equivalent of its chemical group xanthenes, and fluorescein or an equivalent of its chemical group fluoroma, or salts and complexes thereof. The dye compositions are typically present in a aqueous medium.

  本发明涉及一种细胞染料组合物，其特征在于它包括甲基绿或其化学基团三芳基甲烷（或三苯基甲烷）的等效物、pironin或其化学基团氧杂蒽的等效物、荧光素或其化学基团氟马的等效物，或它们的盐和络合物。染料组合物通常存在于水介质中。