(E)-5-(3,4-bis(benzyloxy)phenyl)-2-(3-(4-methylpiperazin-1-yl)styryl)oxazole | 1435232-77-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: (E)-5-(3,4-bis(benzyloxy)phenyl)-2-(3-(4-methylpiperazin-1-yl)styryl)oxazole
• 英文别名: 5-[3,4-bis(phenylmethoxy)phenyl]-2-[(E)-2-[3-(4-methylpiperazin-1-yl)phenyl]ethenyl]-1,3-oxazole
• CAS: 1435232-77-1
• 化学式: C₃₆H₃₅N₃O₃
• 分子量: 557.692
• InChiKey: SCVFHADHVNTMFS-OBGWFSINSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.2
• 重原子数：
  42
• 可旋转键数：
  10
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  51
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  3,4-二苄氧基苯甲醛 在 tris-(dibenzylideneacetone)dipalladium(0) 、 copper(l) iodide 、 trans-1,2-Diethylcyclohexane 、 potassium carbonate 、 sodium t-butanolate 、 lithium tert-butoxide 、 2-二环己基磷-2,4,6-三异丙基联苯 作用下， 以 1,4-二氧六环 、 甲醇 、 甲苯 为溶剂， 生成 (E)-5-(3,4-bis(benzyloxy)phenyl)-2-(3-(4-methylpiperazin-1-yl)styryl)oxazole
  参考文献：
  名称：

  Synthesis and evaluation of photophysical properties of Series of π-conjugated oxazole dyes

  摘要：

  Incorporation of pi-conjugated spacers at the 2 or 5 position of a 2,5-disubstitutedaryloxazole led to new series of fluorescent dyes. They show emissions from visible to 700 nm along with significant Stokes shift up to 208 nm and a strong solvatochromic fluorescence. These compounds are easily accessible in one step through direct C-H bond functionalization. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.04.037

文献信息

• Synthesis and evaluation of photophysical properties of Series of π-conjugated oxazole dyes
  作者：Florence Mahuteau-Betzer、Sandrine Piguel

  DOI：10.1016/j.tetlet.2013.04.037

  日期：2013.6

  Incorporation of pi-conjugated spacers at the 2 or 5 position of a 2,5-disubstitutedaryloxazole led to new series of fluorescent dyes. They show emissions from visible to 700 nm along with significant Stokes shift up to 208 nm and a strong solvatochromic fluorescence. These compounds are easily accessible in one step through direct C-H bond functionalization. (C) 2013 Elsevier Ltd. All rights reserved.