perezinone | 10124-08-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并呋喃
• 英文名称: perezinone
• 英文别名: (5R)-6-hydroxy-2,2,5,8-tetramethyl-4,5-dihydro-2H,3H-naphtho[1,8-bc]furan-7-one；(5R)-6-Hydroxy-2,2,5,8-tetramethyl-4,5-dihydro-2H,3H-naphtho[1,8-bc]furan-7-on；Perezinon；(R)-4,5-Dihydro-6-hydroxy-2,2,5,8-tetramethyl-2H-naphtho[1,8-bc]furan-7(3H)-one；(7R)-9-hydroxy-3,3,7,11-tetramethyl-2-oxatricyclo[6.3.1.04,12]dodeca-1(11),4(12),8-trien-10-one
• CAS: 10124-08-0
• 化学式: C₁₅H₁₈O₃
• 分子量: 246.306
• InChiKey: GPLYVANRJRWDMO-SSDOTTSWSA-N

物化性质

• 熔点：
  166-167 °C
• 沸点：
  424.4±45.0 °C(Predicted)
• 密度：
  1.22±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  羟基三褶菊酮 在 三氟化硼乙醚 作用下， 以 二氯甲烷 为溶剂， 以66%的产率得到perezinone
  参考文献：
  名称：

  Boron trifluoride-catalyzed cycloadditions of naturally occurring sesquiterpene p-benzoquinones

  摘要：

  DOI：

  10.1021/jo00381a010

文献信息

• Inhibition of polymerization of unsaturated monomers
  申请人：——

  公开号：US20020037958A1

  公开（公告）日：2002-03-28

  Disclosed herein is a method for inhibiting the premature polymerization of ethylenically unsaturated monomers comprising adding to said monomers an effective amount of a mixture comprising: A) at least one stable hindered nitroxyl compound having the structural formula: 1 wherein R 1 and R 4 are independently selected from the group consisting of hydrogen, alkyl, and heteroatom-substituted alkyl and R 2 and R 3 are independently selected from the group consisting of alkyl and heteroatom-substituted alkyl; and X 1 and X 2 (1) are independently selected from the group consisting of halogen, cyano, COOR 7 , —S—COR 7 , —OCOR 7 , (wherein R 7 is alkyl or aryl), amido, —S—C 6 H 5 , carbonyl, alkenyl, or alkyl of 1 to 15 carbon atoms, or (2) taken together, form a ring structure with the nitrogen; and B) at least one inhibitor selected from the group consisting of ortho-quinone, ortho-hydroquinone, para-quinone, para-hydroquinone, and derivatives of the foregoing.

  本文公开了一种抑制乙烯基不饱和单体过早聚合的方法，包括向所述单体中加入有效量的混合物，该混合物包括 A) 至少一种具有结构式的稳定受阻硝基化合物： 1 其中 R 1 和 R 4 独立地选自氢、烷基、杂原子取代的烷基和 R 2 和 R 3 独立地选自由烷基和杂原子取代的烷基组成的组；以及 X 1 和 X 2 (1)独立地选自由卤素、氰基、COR 7 、-S-COR 7 、-OCOR 7 ，（其中 R 7 为烷基或芳基）、氨基、-S-C 6 H 5 1至15个碳原子的羰基、烯基或烷基，或(2)合在一起与氮形成环状结构；以及 B) 至少一种选自邻醌、邻氢醌、对苯醌、对氢醌和上述物质的衍生物的抑制剂。
• The structure of β-isopipitzol
  作者：Francisco Yuste、Héctor Barrios、Eduardo Díaz、Benjamín Ortiz、Rubén Sánchez-Obregón、Fernando Walls

  DOI：10.1016/s0040-4039(00)78534-0

  日期：1994.12

  The Lewis acid catalyzed intramolecular cycloaddition of isoperezone (5) produced a tricyclic compound containing a new skeleton named beta-isopipitzol (6), perezinone (7) and dihydroisoperezinone (8).
• INHIBITION OF POLYMERIZATION OF UNSATURATED MONOMERS
  申请人：CROMPTON CORPORATION

  公开号：EP1233937B1

  公开（公告）日：2005-10-26
• US6653414B2
  申请人：——

  公开号：US6653414B2

  公开（公告）日：2003-11-25
• [EN] INHIBITION OF POLYMERIZATION OF UNSATURATED MONOMERS<br/>[FR] INHIBITION DE POLYMERISATION DE MONOMERES INSATURES
  申请人：CROMPTON CORP

  公开号：WO2001040149A2

  公开（公告）日：2001-06-07

  Disclosed herein is a method for inhibiting the premature polymerization of ethylenically unsaturated monomers comprising adding to said monomers an effective amount of a mixture comprising: A) at least one stable hindered nitroxyl compound having structural formula (I) wherein R1 and R4 are independently selected from the group consisting of hydrogen, alkyl, and heteroatom-substituted alkyl and R2 and R3 are independently selected from the group consisting of alkyl and heteroatom-substituted alkyl; and X1 and X2 (1) are independently selected from the group consisting of halogen, cyano, COOR7, -S-COR7, -OCOR7, (wherein R7 is alkyl or aryl), amido, -S-C6H5, carbonyl, alkenyl, or alkyl of 1 to 15 carbon atoms, or (2) taken together, form a ring structure with the nitrogen; and B) at least one inhibitor selected from the group consisting of ortho-quinone, ortho-hydroquinone, para-quinone, para-hydroquinone, and derivatives of the foregoing.