4-Chloro-1-methyl-1H-indazole-3-carbaldehyde | 1033693-09-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡唑类
• 英文名称: 4-Chloro-1-methyl-1H-indazole-3-carbaldehyde
• 英文别名: 4-chloro-1-methylindazole-3-carbaldehyde
• CAS: 1033693-09-2
• 化学式: C₉H₇ClN₂O
• mdl: MFCD10686602
• 分子量: 194.62
• InChiKey: NPZBPERUFKBRQZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.111
• 拓扑面积：
  34.9
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] NOVEL P2X7R ANTAGONISTS AND THEIR USE<br/>[FR] NOUVEAUX ANTAGONISTES DE P2X7R ET LEUR UTILISATION
  申请人：AFFECTIS PHARMACEUTICALS AG

  公开号：WO2009118175A1

  公开（公告）日：2009-10-01

  The present application is directed to novel P2X7R antagonists that are indol-3-carboxamide or azaindole-3-carboxamide compounds, pharmaceutical compositions comprising the same and their use for the prophylactic or therapeutic treatment of diseases mediated by P2X7R activity. Formula (I) - a, b, c, d, x are at each occurrence independently selected from carbon, or nitrogen.