4,5-dinitro-10-azatricyclo[6.3.2.0^2,7]trideca-2(7),3,5-triene | 832089-06-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 4,5-dinitro-10-azatricyclo[6.3.2.0^2,7]trideca-2(7),3,5-triene
• 英文别名: 1,5-Ethano-1H-3-benzazepine, 2,3,4,5-tetrahydro-7,8-dinitro-；4,5-dinitro-10-azatricyclo[6.3.2.02,7]trideca-2,4,6-triene
• CAS: 832089-06-2
• 化学式: C₁₂H₁₃N₃O₄
• 分子量: 263.253
• InChiKey: NMVXMYZQFGDBEA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  19
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  104
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Aryl fused azapolycyclic compounds
  申请人：Coe W. Jotham

  公开号：US20050020616A1

  公开（公告）日：2005-01-27

  This invention is directed to compounds of the formula (I): and their pharmaceutically acceptable salts, wherein R 1 , R 2 , R 3 and Z are as defined herein; intermediates for the synthesis of such compounds, pharmaceutical compositions containing such compounds; and methods of using such compounds in the treatment of neurological and psychological disorders.

  本发明涉及式(I)的化合物及其药用盐，其中R1、R2、R3和Z如本文所定义；用于合成这类化合物的中间体，含有这类化合物的药物组合物；以及使用这类化合物治疗神经和心理障碍的方法。
• ARYL FUSED AZAPOLYCYCLIC COMPOUNDS
  申请人：Pfizer Products Inc.

  公开号：EP1648872A2

  公开（公告）日：2006-04-26
• [EN] ARYL FUSED AZAPOLYCYCLIC COMPOUNDS<br/>[FR] COMPOSES AZAPOLYCYCLIQUES FUSIONNES AVEC ARYLE
  申请人：PFIZER PROD INC

  公开号：WO2005007630A2

  公开（公告）日：2005-01-27

  This invention is directed to compounds of the formula (I): and their pharmaceutically acceptable salts, wherein R1, R2, R3 and Z are as defined herein; intermediates for the synthesis of such compounds, pharmaceutical compositions containing such compounds; and methods of using such compounds in the treatment of neurological and psychological disorders.