Edb7R887G3 | 1007853-40-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 萘并吡喃类
• 英文名称: Edb7R887G3
• 英文别名: 2,8-dihydroxy-6H-naphtho[1,2-c]isochromene-4,12-dicarbonitrile
• CAS: 1007853-40-8
• 化学式: C₁₉H₁₀N₂O₃
• 分子量: 314.3
• InChiKey: UGZYFAJTTRGNOX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  24
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  97.3
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• Method for treating or preventing a cardiovascular disease or condition utilizing estrogen receptor modulators based on APOE allelic profile of a mammalian subject
  申请人：Hyde Roderick A.

  公开号：US20100022497A1

  公开（公告）日：2010-01-28

  A method for treating cardiovascular disease in a mammalian subject includes providing to the subject at least one treatment regimen including at least one estrogen receptor modulator, wherein the at least one treatment regimen is determined based on the APOE allelic profile in the subject, and based on the steroid hormone levels prior to disease diagnosis and on current steroid hormone levels in the subject.
• Method for treating or preventing osteoporosis by reducing follicle stimulating hormone to cyclic physiological levels in a mammalian subject
  申请人：Ishikawa Muriel Y.

  公开号：US20100092463A1

  公开（公告）日：2010-04-15

  A method is described for treating or preventing a bone loss disease or a bone loss disorder in a mammalian subject or reducing the incidence of a bone loss disease or a bone loss disorder or alleviating the symptoms thereof. The method includes providing to the mammalian subject at least one treatment regimen including at least one follicle-stimulating hormone modulator configured to and in an amount sufficient to reduce bioactivity or bioavailability of follicle-stimulating hormone in the mammalian subject.