ZINC;4-(4-nitrophenyl)piperazine-1-carbodithioate | 588691-97-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: ZINC;4-(4-nitrophenyl)piperazine-1-carbodithioate
• CAS: 588691-97-8
• 化学式: C₂₂H₂₄N₆O₄S₄Zn
• 分子量: 630.124
• InChiKey: BXSYIKZVJLZZIX-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  3.09
• 重原子数：
  37
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  171
• 氢给体数：
  0
• 氢受体数：
  10

反应信息

• 作为产物：
  描述：

  zinc(II) nitrate 、 nitrophenylpiperazine dithiocarbamate potassium salt 以84%的产率得到ZINC;4-(4-nitrophenyl)piperazine-1-carbodithioate
  参考文献：
  名称：

  Metal Complexes of Phenylpiperazine‐Based Dithiocarbamate Ligands. Synthesis, Characterization, Spectroscopic, Thermal, and Antimicrobial Activity Studies

  摘要：

  Potassium salts of phenylpiperazine (Phpzdtc), fluorophenylpiperazine (F-Phpzdtc) and nitrophenylpiperazine (N-Phpzdtc) dithiocarbamates and their manganese(II), iron(II), cobalt(II), nickel(II), copper(II) and zinc(II) complexes have been synthesized and characterized by elemental analyses, IR, UV-VIS, magnetic moment measurements and thermal analysis techniques. On the basis of experimental data, the dithiocarbamates (dtcs) have been observed to coordinate to the metal ions via both sulphur atoms of the -NCS2 group forming metal complexes with a metal to ligand ratio of 1:2. The thermal reactivity and antimicrobial activity of the ligands and their metal complexes were also studied. The decomposition of the metal complexes resulted in the formation of the corresponding metal thiocyanates or cyanates as stable intermediates. Phpzdtc was found to be microbiologically more active than its nitro and fluoro derivatives and biological activity of the dtc ligands either remained unaltered or decreased on complexation with metal ions.

  DOI：

  10.1081/sim-120020326

文献信息

• Metal Complexes of Phenylpiperazine‐Based Dithiocarbamate Ligands. Synthesis, Characterization, Spectroscopic, Thermal, and Antimicrobial Activity Studies
  作者：Veysel T. Yilmaz、Turan K. Yazıcılar、Hasan Cesur、Resit Ozkanca、Fatma Z. Maras

  DOI：10.1081/sim-120020326

  日期：2003.1.6

  Potassium salts of phenylpiperazine (Phpzdtc), fluorophenylpiperazine (F-Phpzdtc) and nitrophenylpiperazine (N-Phpzdtc) dithiocarbamates and their manganese(II), iron(II), cobalt(II), nickel(II), copper(II) and zinc(II) complexes have been synthesized and characterized by elemental analyses, IR, UV-VIS, magnetic moment measurements and thermal analysis techniques. On the basis of experimental data, the dithiocarbamates (dtcs) have been observed to coordinate to the metal ions via both sulphur atoms of the -NCS2 group forming metal complexes with a metal to ligand ratio of 1:2. The thermal reactivity and antimicrobial activity of the ligands and their metal complexes were also studied. The decomposition of the metal complexes resulted in the formation of the corresponding metal thiocyanates or cyanates as stable intermediates. Phpzdtc was found to be microbiologically more active than its nitro and fluoro derivatives and biological activity of the dtc ligands either remained unaltered or decreased on complexation with metal ions.