4-Ethyl-isochroman-3-ol | 1025987-55-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 4-Ethyl-isochroman-3-ol
• 英文别名: 4-ethyl-3,4-dihydro-1H-isochromen-3-ol
• CAS: 1025987-55-6
• 化学式: C₁₁H₁₄O₂
• 分子量: 178.231
• InChiKey: HDRBVMHZHOPHFH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-Ethyl-isochroman-3-ol 在 甲基磺酰氯 作用下， 生成 4-Ethyl-1H-isochromene
  参考文献：
  名称：

  Synthesis of Optically Active .alpha.-Hydroxy Lactones by Sharpless Asymmetric Dihydroxylations of Ketene Acetals, Enol Ethers, and Ene Lactones

  摘要：

  Three different AD routes to optically active alpha-hydroxy lactones of good to excellent optical purity are reported. The substrates for the AD reaction are endocyclic ketene acetals, endocyclic enol ethers, and exocyclic alpha,beta-unsaturated lactones.

  DOI：

  10.1021/jo00100a005
• 作为产物：
  描述：

  4-Ethyl-isochroman-3-one 在 二异丁基氢化铝 作用下， 生成 4-Ethyl-isochroman-3-ol
  参考文献：
  名称：

  Synthesis of Optically Active .alpha.-Hydroxy Lactones by Sharpless Asymmetric Dihydroxylations of Ketene Acetals, Enol Ethers, and Ene Lactones

  摘要：

  Three different AD routes to optically active alpha-hydroxy lactones of good to excellent optical purity are reported. The substrates for the AD reaction are endocyclic ketene acetals, endocyclic enol ethers, and exocyclic alpha,beta-unsaturated lactones.

  DOI：

  10.1021/jo00100a005

文献信息

• Synthesis of Optically Active .alpha.-Hydroxy Lactones by Sharpless Asymmetric Dihydroxylations of Ketene Acetals, Enol Ethers, and Ene Lactones
  作者：Dennis P. Curran、Sung-Bo Ko

  DOI：10.1021/jo00100a005

  日期：1994.10

  Three different AD routes to optically active alpha-hydroxy lactones of good to excellent optical purity are reported. The substrates for the AD reaction are endocyclic ketene acetals, endocyclic enol ethers, and exocyclic alpha,beta-unsaturated lactones.