3-乙基-1-氯环己烷 | 60908-36-3

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代烷
• 中文名称: 3-乙基-1-氯环己烷
• 英文名称: 3-ethyl-1-chlorocyclohexane
• 英文别名: 1-Chloro-3-ethylcyclohexane
• CAS: 60908-36-3
• 化学式: C₈H₁₅Cl
• 分子量: 146.66
• InChiKey: KADHMPAPWWGSGE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  顺-环辛烯 在 二氯甲烷 、 RhCl(PPh₃)3 作用下， 反应 5.0h， 生成 氯环辛烷 、 4-乙基-1-氯环己烷 、 3-乙基-1-氯环己烷
  参考文献：
  名称：

  Hydrochlorination of unsaturated compounds by the action of CH2Cl2 or CHCl3 and rhodium complexes

  摘要：

  A new method has been developed for the catalytic hydrochlorination of olefins and acetylenes in the presence of Rh complexes by means of HCl generated in situ from CH2Cl2 and CHCl3 under the reaction conditions. The reaction was studied using the hydrochlorination of propylene, 1-hexene, 1-nonene, vinylcyclopropane, 1,1-dicyclopropylethylene, cyclohexene, cyclooctene, norbornene, and 1,5-cyclooctadiene as examples.

  DOI：

  10.1007/bf00961299

文献信息

• [EN] FLUORENE-9-BISPHENOL COMPOUNDS AND METHODS FOR THEIR USE<br/>[FR] COMPOSÉS DE FLUORÈNE-9-BISPHÉNOL ET LEURS MÉTHODES D'UTILISATION
  申请人：UNIV BRITISH COLUMBIA

  公开号：WO2012145330A1

  公开（公告）日：2012-10-26

  Compounds having a structure of Formula I: or a pharmaceutically acceptable salt or tautomer thereof, wherein Z1, Z2, Z3 and Z4 are as defined herein. Uses of such compounds for treatment of various indications, including prostate cancer as well as methods of treatment involving such compounds are also provided.

  具有以下结构的化合物：或其药用可接受的盐或互变异构体，其中Z1、Z2、Z3和Z4如本文所定义。提供了这些化合物用于治疗各种适应症，包括前列腺癌的用途，以及涉及这些化合物的治疗方法。
• [EN] DIGLYCIDIC ETHER DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE<br/>[FR] PRODUITS THÉRAPEUTIQUES DÉRIVÉS D'ÉTHERS DIGLYCIDIQUES ET LEURS PROCÉDÉS D'UTILISATION
  申请人：BRITISH COLUMBIA CANCER AGENCY

  公开号：WO2010000066A1

  公开（公告）日：2010-01-07

  This invention provides compound having a structure of Formula I or Formula II. Uses of such compounds for treatment of various indications, including prostate cancer as well as methods of treatment involving such compounds are also provided.

  这项发明提供了具有化学结构为式I或式II的化合物。还提供了这些化合物用于治疗各种适应症，包括前列腺癌的用途，以及涉及这些化合物的治疗方法。
• [EN] SMALL MOLECULE INHIBITORS OF N-TERMINUS ACTIVATION OF THE ANDROGEN RECEPTOR<br/>[FR] PETITS INHIBITEURS MOLÉCULAIRES DE L'ACTIVATION DU TERMINAL-N DU RÉCEPTEUR ANDROGÈNE
  申请人：BRITISH COLUMBIA CANCER AGENCY

  公开号：WO2010020055A1

  公开（公告）日：2010-02-25

  Compounds having a structure of Formula (A) are provided. Uses of such compounds for treatment of various indications, including prostate cancer as well as methods of treatment involving such compounds are provided. Uses of compounds having a structure of Formula (F) for treatment of various indications, including prostate cancer as well as methods of treatment involving such compounds are also provided.

  提供了具有公式（A）结构的化合物。提供了这些化合物用于治疗各种适应症，包括前列腺癌的用途，以及涉及这些化合物的治疗方法。还提供了具有公式（F）结构的化合物用于治疗各种适应症，包括前列腺癌的用途，以及涉及这些化合物的治疗方法。
• [EN] BISPHENOL DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE<br/>[FR] AGENTS THÉRAPEUTIQUES À BASE DE DÉRIVÉS DU BISPHÉNOL ET MÉTHODES POUR LEUR UTILISATION
  申请人：BRITISH COLUMBIA CANCER AGENCY

  公开号：WO2011082488A1

  公开（公告）日：2011-07-14

  This invention provides compounds having a structure of Formula (I). Uses of such compounds for treatment of various indications, including prostate cancer as well as methods of treatment involving such compounds are also provided.

  本发明提供具有公式（I）结构的化合物。这些化合物的用途包括治疗多种适应症，包括前列腺癌，同时还提供了涉及这些化合物的治疗方法。
• [EN] DIBENZYLPHENYL COMPOUNDS AND METHODS FOR THEIR USE<br/>[FR] COMPOSÉS DE DIBENZYLPHÉNYLE ET LEURS MÉTHODES D'UTILISATION
  申请人：UNIV BRITISH COLUMBIA

  公开号：WO2012145328A1

  公开（公告）日：2012-10-26

  Compounds having a structure of Formula I: or a pharmaceutically acceptable salt thereof, wherein Z1, Z2, R1 and R2 are as defined herein are provided. Uses of such compounds for treatment of various indications, including prostate cancer as well as methods of treatment involving such compounds are also provided.

  提供具有以下结构的化合物I或其药学上可接受的盐，其中Z1、Z2、R1和R2的定义如本文所述。提供了这种化合物用于治疗各种适应症的用途，包括前列腺癌以及涉及这种化合物的治疗方法。